NLRP3 Inflammasome in the Pathophysiology of Hemorrhagic Stroke: A Review
Sign Up to like & getrecommendations! Published in 2018 at "Current Neuropharmacology"
DOI: 10.2174/1570159x17666181227170053
Abstract: Hemorrhagic stroke is a devastating disease with high morbidity and mortality. There is still a lack of effective ther-apeutic approach. The recent studies have shown that the innate immune system plays a significant role in… read more here.
Keywords: stroke review; hemorrhagic stroke; inflammasome pathophysiology; nlrp3 inflammasome ... See more keywords
NLRP3 Inflammasome: From Pathophysiology to Therapeutic Target in Major Depressive Disorder
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010133
Abstract: Major depressive disorder (MDD) is a highly prevalent psychiatric disorder, whose pathophysiology has been linked to the neuroinflammatory process. The increased activity of the Nod-like receptor pyrin containing protein 3 (NLRP3) inflammasome, an intracellular multiprotein… read more here.
Keywords: nlrp3 inflammasome; depressive disorder; disorder; inflammasome pathophysiology ... See more keywords