A novel inflammasome-related gene nomogram predicts survival in hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033121
Abstract: Inflammasomes are closely associated with the progression of multiple cancers. We established an inflammasome-related gene (IRG)-based model to predict the survival of patients with hepatocellular carcinoma (HCC). The RNA-sequencing data and clinical information of HCC… read more here.
Keywords: hepatocellular carcinoma; inflammasome related; model; related gene ... See more keywords
Inflammasome-related Markers upon ICU Admission do not Correlate with Outcome in Critically Ill COVID-19 Patients
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DOI: 10.1097/shk.0000000000001923
Abstract: ABSTRACT Purpose: The development of targeted biological therapies for coronavirus disease 2019 (COVID-19) requires reliable biomarkers that could help indicate how patients are responding. The hyperactivation of inflammasomes by the SARS-CoV2 virus is hypothesized to… read more here.
Keywords: inflammasome related; critically ill; covid patients; ill covid ... See more keywords
Relevance of NLRP3 Inflammasome-Related Pathways in the Pathology of Diabetic Wound Healing and Possible Therapeutic Targets
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/9687925
Abstract: Wound healing is a major secondary complication in type 2 diabetes, which results in significant disability and mortality, imposing a significant clinical and social burden. Sustained activation of the Nod-like receptor protein (NLRP) inflammasome in… read more here.
Keywords: related pathways; inflammasome related; wound healing; inflammasome ... See more keywords
Parthenolide targets NLRP3 to treat inflammasome-related diseases.
Sign Up to like & getrecommendations! Published in 2023 at "International immunopharmacology"
DOI: 10.2139/ssrn.4352824
Abstract: Natural products have attracted extensive attention from researchers in medical fields due to their abundant biological activities. Parthenolide (PTL) is a sesquiterpene lactone originally purified from herb Feverfew (Tanacetum parthenium), recent studies have showed its… read more here.
Keywords: inflammasome related; inflammasome; targets nlrp3; related diseases ... See more keywords
Investigating regulatory patterns of NLRP3 Inflammasome features and association with immune microenvironment in Crohn’s disease
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DOI: 10.3389/fimmu.2022.1096587
Abstract: Introduction Crohn’s disease is characterized of dysregulated inflammatory and immune reactions. The role of the NOD-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome in Crohn’s disease remains largely unknown. Methods The microarray-based transcriptomic data and… read more here.
Keywords: inflammasome related; disease; crohn disease; related genes ... See more keywords
Increased Serum Levels of Growth-Differentiation Factor 3 (GDF3) and Inflammasome-Related Markers in Pregnant Women during Acute Zika Virus Infection
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DOI: 10.3390/v14051004
Abstract: The systemic inflammatory response elicited by acute Zika virus (ZIKV) infection during pregnancy plays a key role in the clinical outcomes in mothers and congenitally infected offspring. The present study aimed to evaluate the serum… read more here.
Keywords: inflammasome related; women acute; infection; pregnant women ... See more keywords