Articles with "inflammation" as a keyword



Association of Systemic Inflammation and Sarcopenia With Survival in Nonmetastatic Colorectal Cancer: Results From the C SCANS Study

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Published in 2017 at "JAMA Oncology"

DOI: 10.1001/jamaoncol.2017.2319

Abstract: Importance Systemic inflammation and sarcopenia are easily evaluated, predict mortality in many cancers, and are potentially modifiable. The combination of inflammation and sarcopenia may be able to identify patients with early-stage colorectal cancer (CRC) with… read more here.

Keywords: sarcopenia; inflammation; cancer; crc ... See more keywords

Gene Expression Profiling and Heterogeneity of Nonspecific Orbital Inflammation Affecting the Lacrimal Gland

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Published in 2017 at "JAMA Ophthalmology"

DOI: 10.1001/jamaophthalmol.2017.3458

Abstract: Importance Although a variety of well-characterized diseases, such as sarcoidosis and granulomatosis with polyangiitis, affect the lacrimal gland, many patients with dacryoadenitis are diagnosed as having nonspecific orbital inflammation (NSOI) on the basis of histology… read more here.

Keywords: biopsy specimens; expression; inflammation; gene expression ... See more keywords
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Performing Pain and Inflammation: Rendering the Invisible Visible.

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Published in 2017 at "AMA journal of ethics"

DOI: 10.1001/journalofethics.2017.19.8.imhl1-1708

Abstract: These drawings represent everyday experiences of an artist who has been living with rheumatoid arthritis since her teenage years. Over the course of 20 years, the disease has damaged a series of joints in her… read more here.

Keywords: invisible visible; performing pain; inflammation; rendering invisible ... See more keywords

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer.

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Published in 2025 at "Molecular oncology"

DOI: 10.1002/1878-0261.70067

Abstract: High‐grade serous ovarian carcinoma (HGSOC) associates with the worst patient outcome. Understanding the tumor environment in terms of quantifying endogenous retroviruses (ERVs) and LINE‐1 expression and their correlations with inflammation genes, checkpoint inhibitors and patient… read more here.

Keywords: line expression; tumor; inflammation; expression ... See more keywords

Fatostatin ameliorates inflammation without affecting cell viability

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Published in 2022 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13364

Abstract: The mature form of sterol regulatory element‐binding protein (SREBP)1 is a transcription factor involved in lipid synthesis, which participates in toll like receptor 4‐triggered inflammatory pathways during the resolution phase of inflammation in macrophages. SREBP1… read more here.

Keywords: affecting cell; fatostatin; cell viability; inflammation ... See more keywords

Inflammation‐Instructed Hierarchical Delivery of IL‐4/miR‐21 Orchestrates Osteoimmune Microenvironment toward the Treatment of Rheumatoid Arthritis

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Published in 2021 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202101033

Abstract: Dysregulated inflammation and failure in resolution account for the incidence and deterioration of rheumatoid arthritis (RA). IL‐4 and miR‐21 possess complementary functions in inhibiting inflammation and fostering resolution. Thus, inflammation‐instructed nanocomplexes (NCs) are herein developed… read more here.

Keywords: arthritis; mir; delivery mir; microenvironment ... See more keywords

Silk Sericin‐based ROS‐Responsive Oxygen Generating Microneedle Platform Promotes Angiogenesis and Decreases Inflammation for Scarless Diabetic Wound Healing

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Published in 2024 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202404461

Abstract: Diabetic foot ulcer typically undergoes a delayed wound‐healing process owing to the disordered microenvironment, including persistent inflammation, long‐term hypoxia, and excessive fibrosis, eventually leading to severe disabilities and other poor outcomes. However, current strategies cannot… read more here.

Keywords: oxygen; diabetic wound; wound healing; microneedle platform ... See more keywords

Inflammatory Microenvironment‐Responsive Nanomotors with NIR Photothermal Effect for Deep Inflammation Elimination and Infection Inhibition

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Published in 2024 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202416684

Abstract: The infected chronic wound area has a unique microenvironment featuring hypoxia, excessive reactive oxygen species (ROS), and inflammatory conditions. Bacteria‐formed biofilms limit the anti‐inflammation efficiency of most therapeutics by hindering their penetration into deep infected… read more here.

Keywords: microenvironment responsive; nanomotors nir; nir photothermal; inflammation ... See more keywords

Robust Injectable Hydrogels for Hemophilic Arthropathy via Anti‐Inflammation, Iron Removal and Cartilage Protection

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Published in 2025 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202500271

Abstract: Hemophilic arthropathy (HA), a form of arthritis associated with joint bleeding, presents extra challenges in treatment due to intermittent bleeding‐induced iron‐overloading, oxidative stress, and inflammation. Conventional therapeutic approaches have predominantly concentrated on achieving hemostasis and… read more here.

Keywords: iron; hemophilic arthropathy; injectable hydrogels; inflammation ... See more keywords

Photothermal Wood Biopatch Clears Toxins and Exudate to Heal Wounds

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Published in 2025 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202515975

Abstract: Bacteria‐infected wound often emerges with accumulation of dense exudates and toxins such as lipopolysaccharide (LPS) and peptidoglycan (PGN) released by bacteria, creating a vicious cycle of nutrient enrichment, bacterial proliferation, and toxin‐induced inflammation that aggravates… read more here.

Keywords: pro biop; wood biopatch; photothermal wood; wood ... See more keywords
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Mesopore to Macropore Transformation of Metal-Organic Framework for Drug Delivery in Inflammatory Bowel Disease.

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Published in 2020 at "Advanced healthcare materials"

DOI: 10.1002/adhm.202000973

Abstract: Inflammatory bowel disease (IBD) is a chronic relapsing autoimmune disease that is characterized by segmental intestinal inflammation. There is an urgent need for more efficient inflammation-targeting strategies to improve therapeutic effect and reduce systemic drug… read more here.

Keywords: bowel disease; inflammatory bowel; delivery; inflammation ... See more keywords