Diacylglycerol kinase ζ promotes allergic airway inflammation and airway hyperresponsiveness through distinct mechanisms
Sign Up to like & getrecommendations! Published in 2019 at "Science Signaling"
DOI: 10.1126/scisignal.aax3332
Abstract: Allergic inflammation and airway hyperresponsiveness in asthma are independently exacerbated by DGK activity. DGKζ activates airways Asthma is characterized by both T cell–mediated inflammation and airway smooth muscle cell hyperreactivity. In T cells, activation stimulates… read more here.
Keywords: dgk; inflammation; airway inflammation; inflammation airway ... See more keywords
TRIM33 Modulates Inflammation and Airway Remodeling of PDGF-BB-Induced Airway Smooth-Muscle Cells by the Wnt/β-Catenin Pathway
Sign Up to like & getrecommendations! Published in 2022 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000524574
Abstract: Asthma is a chronic airway disease involving airway inflammation and remodeling. Studies showed that tripartite motif-containing protein 33 (TRIM33) regulated natural immunity, inflammation, and pulmonary fibrosis. However, the role and regulatory mechanism of TRIM33 in… read more here.
Keywords: trim33; wnt catenin; airway remodeling; inflammation airway ... See more keywords
Prophylactic Supplementation of Bifidobacterium longum 51A Protects Mice from Ovariectomy-Induced Exacerbated Allergic Airway Inflammation and Airway Hyperresponsiveness
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2017.01732
Abstract: Asthma is a chronic inflammatory disease that affects more females than males after puberty, and its symptoms and severity in women change during menstruation and menopause. Recently, evidence has demonstrated that interactions among the microbiota,… read more here.
Keywords: inflammation; airway inflammation; longum 51a; inflammation airway ... See more keywords
Overview of the Mechanisms of Oxidative Stress: Impact in Inflammation of the Airway Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11112237
Abstract: Inflammation of the human lung is mediated in response to different stimuli (e.g., physical, radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental pollutants. They often promote an increase in inflammatory activities in… read more here.
Keywords: inflammation; overview mechanisms; oxidative stress; inflammation airway ... See more keywords
Mesenchymal Stem Cells Attenuate Asthmatic Inflammation and Airway Remodeling by Modulating Macrophages/Monocytes in the IL-13-Overexpressing Mouse Model
Sign Up to like & getrecommendations! Published in 2022 at "Immune Network"
DOI: 10.4110/in.2022.22.e40
Abstract: Mesenchymal stem cells (MSCs) are attractive alternatives to conventional anti-asthmatic drugs for severe asthma. Mechanisms underlying the anti-asthmatic effects of MSCs have not yet been elucidated. This study evaluated the anti-asthmatic effects of intravenously administered… read more here.
Keywords: inflammation; inflammation airway; mesenchymal stem; mscs ... See more keywords