Increased SERPINB10 Expression in Induced Sputum Was Associated with Airway Type 2 Inflammation in Asthma
Sign Up to like & getrecommendations! Published in 2022 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000524613
Abstract: Background: Asthma is a common chronic airway inflammation in the world. The aim of this study was to investigate the expression of SERPINB10 in induced sputum and its correlation with airway type 2 inflammation in… read more here.
Keywords: induced sputum; airway type; type inflammation; inflammation ... See more keywords
A Network of Sputum MicroRNAs is Associated with Neutrophilic Airway Inflammation in Asthma.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.201912-2360oc
Abstract: BACKGROUND MicroRNAs are potent regulators of biologic systems that are critical to tissue homeostasis. However, a systems analysis of the microRNA-mRNA networks present in the sputum that contribute to airway inflammation in asthma has not… read more here.
Keywords: airway inflammation; sputum micrornas; inflammation asthma; sputum ... See more keywords
Charcot-Leyden crystal protein/galectin-10 is a surrogate biomarker of eosinophilic airway inflammation in asthma.
Sign Up to like & getrecommendations! Published in 2019 at "Biomarkers in medicine"
DOI: 10.2217/bmm-2018-0280
Abstract: Aim: Eosinophilic asthma is associated with more exacerbations and differential responses to treatment. The aim of this study was to assess if CLC/Gal-10 and MBP-1 are surrogate biomarkers of eosinophilic inflammation in asthma. Methods & results:… read more here.
Keywords: gal mbp; inflammation asthma; eosinophilic airway; clc gal ... See more keywords
Inflammation in Asthma: Mechanistic Insights and the Role of Biologics in Therapeutic Frontiers
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DOI: 10.3390/biomedicines13061342
Abstract: Asthma is a chronic and multifaceted respiratory condition that affects over 300 million individuals across the globe. It is characterized by persistent inflammation of the airways, which leads to episodes of wheezing, breathlessness, chest tightness,… read more here.
Keywords: high asthma; low asthma; inflammation asthma; asthma mechanistic ... See more keywords