Articles with "inflammation immunity" as a keyword



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Prognostic value of inflammation‐immunity‐nutrition score in patients with hepatocellular carcinoma treated with anti‐PD‐1 therapy

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Published in 2022 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.24336

Abstract: There are no validated biomarkers that can predict the clinical benefit of immune checkpoint blockers against the programmed cell death protein 1 (PD‐1) treatments in hepatocellular carcinoma (HCC). This study aimed to investigate the prognostic… read more here.

Keywords: hepatocellular carcinoma; value inflammation; inflammation immunity; immunity nutrition ... See more keywords
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Inflammation, Immunity, and Vaccine Development for the Gastric Pathogen Helicobacter pylori.

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Published in 2019 at "Current topics in microbiology and immunology"

DOI: 10.1007/978-3-030-15138-6_1

Abstract: It has been over 30 years since a link was established between H. pylori infection of the gastric mucosa and the development of chronic gastric diseases. Research in rodent models supported by data from human tissue… read more here.

Keywords: immunity vaccine; infection; inflammation immunity; development ... See more keywords
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Promising new therapeutic targets for regulation of inflammation and immunity: RING-type E3 ubiquitin ligases.

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Published in 2018 at "Immunology letters"

DOI: 10.1016/j.imlet.2018.08.001

Abstract: Ubiquitin-proteasome system (UPS) is a primary signaling pathway for regulation of protein turnover and removal of misfolded proteins in eukaryotic cells. Enzymes of the UPS pathway - E1 activating, E2 conjugating, E3 ligating - act… read more here.

Keywords: ring type; type ubiquitin; inflammation immunity; ubiquitin ligases ... See more keywords
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RIP kinases as modulators of inflammation and immunity

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Published in 2018 at "Nature Immunology"

DOI: 10.1038/s41590-018-0188-x

Abstract: Receptor-interacting protein (RIP) kinases, in particular RIPK1, RIPK2 and RIPK3, have emerged as pleiotropic modulators of inflammatory responses that act either by directly regulating intracellular inflammatory signaling pathways or by causing apoptotic or necrotic cell… read more here.

Keywords: modulators inflammation; inflammation immunity; rip; kinases modulators ... See more keywords
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Prognostic Value of Inflammation-Immunity-Nutrition Score and Inflammatory Burden Index for Hepatocellular Carcinoma Patients After Hepatectomy

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Published in 2022 at "Journal of Inflammation Research"

DOI: 10.2147/jir.s386407

Abstract: Purpose The study aimed to investigate the ability of inflammation-immunity-nutrition score (IINS) and inflammatory burden index (IBI), individually or in combination, to predict prognosis of hepatocellular carcinoma (HCC) patients after hepatectomy. Methods A total of… read more here.

Keywords: patients hepatectomy; prognostic value; index; inflammation immunity ... See more keywords
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Alpha-2-Macroglobulin in Inflammation, Immunity and Infections

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Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.803244

Abstract: Alpha-2-macroglobulin is an extracellular macromolecule mainly known for its role as a broad-spectrum protease inhibitor. By presenting itself as an optimal substrate for endopeptidases of all catalytic types, alpha-2-macroglobulin lures active proteases into its molecular… read more here.

Keywords: immunity infections; inflammation immunity; alpha macroglobulin;
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Role of inflammation, immunity, and oxidative stress in hypertension: New insights and potential therapeutic targets

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1098725

Abstract: Hypertension is regarded as the most prominent risk factor for cardiovascular diseases, which have become a primary cause of death, and recent research has demonstrated that chronic inflammation is involved in the pathogenesis of hypertension.… read more here.

Keywords: inflammation; inflammation immunity; oxidative stress; hypertension ... See more keywords
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The prognostic significance of inflammation-immunity-nutrition score on postoperative survival and recurrence in hepatocellular carcinoma patients

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.913731

Abstract: Background Inflammation, immunity, and nutrition status play important roles in tumorigenesis, progression, and metastasis. This study aimed to evaluate the prognostic value of Inflammation-Immunity-Nutrition Score (IINS) for overall survival (OS) and progression-free survival (PFS) in… read more here.

Keywords: inflammation immunity; immunity nutrition; iins afp; month auc ... See more keywords
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A Review of Signaling Transduction Mechanisms in Osteoclastogenesis Regulation by Autophagy, Inflammation, and Immunity

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23179846

Abstract: Osteoclastogenesis is an ongoing rigorous course that includes osteoclast precursors fusion and bone resorption executed by degradative enzymes. Osteoclastogenesis is controlled by endogenous signaling and/or regulators or affected by exogenous conditions and can also be… read more here.

Keywords: signaling transduction; inflammation immunity; autophagy inflammation; review signaling ... See more keywords
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Host-Related Factors in the Interplay among Inflammation, Immunity and Dormancy in Breast Cancer Recurrence and Prognosis: An Overview for Clinicians

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24054974

Abstract: A significant proportion of patients treated for early breast cancer develop medium-term and late distant recurrence. The delayed manifestation of metastatic disease is defined as “dormancy”. This model describes the aspects of the clinical latency… read more here.

Keywords: dormancy; breast cancer; inflammation immunity; cancer ... See more keywords
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Pruritus as a Distinctive Feature of Type 2 Inflammation

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Published in 2021 at "Vaccines"

DOI: 10.3390/vaccines9030303

Abstract: Pruritus is a common symptom of several skin diseases, both inflammatory and neoplastic. Pruritus might have a tremendous impact on patients’ quality of life and strongly interfere with sleep, social, and work activities. We review… read more here.

Keywords: type inflammation; inflammation; pruritus; inflammation immunity ... See more keywords