Prognostic value of inflammation‐immunity‐nutrition score in patients with hepatocellular carcinoma treated with anti‐PD‐1 therapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24336
Abstract: There are no validated biomarkers that can predict the clinical benefit of immune checkpoint blockers against the programmed cell death protein 1 (PD‐1) treatments in hepatocellular carcinoma (HCC). This study aimed to investigate the prognostic… read more here.
Keywords: hepatocellular carcinoma; value inflammation; inflammation immunity; immunity nutrition ... See more keywords
Inflammation, Immunity, and Vaccine Development for the Gastric Pathogen Helicobacter pylori.
Sign Up to like & getrecommendations! Published in 2019 at "Current topics in microbiology and immunology"
DOI: 10.1007/978-3-030-15138-6_1
Abstract: It has been over 30 years since a link was established between H. pylori infection of the gastric mucosa and the development of chronic gastric diseases. Research in rodent models supported by data from human tissue… read more here.
Keywords: immunity vaccine; infection; inflammation immunity; development ... See more keywords
Promising new therapeutic targets for regulation of inflammation and immunity: RING-type E3 ubiquitin ligases.
Sign Up to like & getrecommendations! Published in 2018 at "Immunology letters"
DOI: 10.1016/j.imlet.2018.08.001
Abstract: Ubiquitin-proteasome system (UPS) is a primary signaling pathway for regulation of protein turnover and removal of misfolded proteins in eukaryotic cells. Enzymes of the UPS pathway - E1 activating, E2 conjugating, E3 ligating - act… read more here.
Keywords: ring type; type ubiquitin; inflammation immunity; ubiquitin ligases ... See more keywords
RIP kinases as modulators of inflammation and immunity
Sign Up to like & getrecommendations! Published in 2018 at "Nature Immunology"
DOI: 10.1038/s41590-018-0188-x
Abstract: Receptor-interacting protein (RIP) kinases, in particular RIPK1, RIPK2 and RIPK3, have emerged as pleiotropic modulators of inflammatory responses that act either by directly regulating intracellular inflammatory signaling pathways or by causing apoptotic or necrotic cell… read more here.
Keywords: modulators inflammation; inflammation immunity; rip; kinases modulators ... See more keywords
Inflammation and Immunity in Liver Neoplasms: Implications for Future Therapeutic Strategies.
Sign Up to like & getrecommendations! Published in 2024 at "Molecular cancer therapeutics"
DOI: 10.1158/1535-7163.mct-23-0726
Abstract: Over the past two decades, the "hallmarks of cancer" have revolutionized cancer research and highlighted the crucial roles of inflammation and immunity. Pro-tumorigenic inflammation promotes cancer development along with inhibition of anti-tumor immunity, shaping the… read more here.
Keywords: cancer; liver neoplasms; liver cancer; liver ... See more keywords
Prognostic Value of Inflammation-Immunity-Nutrition Score and Inflammatory Burden Index for Hepatocellular Carcinoma Patients After Hepatectomy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s386407
Abstract: Purpose The study aimed to investigate the ability of inflammation-immunity-nutrition score (IINS) and inflammatory burden index (IBI), individually or in combination, to predict prognosis of hepatocellular carcinoma (HCC) patients after hepatectomy. Methods A total of… read more here.
Keywords: patients hepatectomy; prognostic value; index; inflammation immunity ... See more keywords
A Nomogram Model Based on the Inflammation-Immunity-Nutrition Score (IINS) and Classic Clinical Indicators for Predicting Prognosis in Extranodal Natural Killer/T-Cell Lymphoma
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s452521
Abstract: Background Systemic inflammation, immunity, and nutritional status are closely related to patients’ outcomes in several kinds of cancers. This study aimed to establish a new nomogram based on inflammation-immunity-nutrition score (IINS) to predict the prognosis… read more here.
Keywords: cohort; based inflammation; prognosis; inflammation ... See more keywords
Alpha-2-Macroglobulin in Inflammation, Immunity and Infections
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.803244
Abstract: Alpha-2-macroglobulin is an extracellular macromolecule mainly known for its role as a broad-spectrum protease inhibitor. By presenting itself as an optimal substrate for endopeptidases of all catalytic types, alpha-2-macroglobulin lures active proteases into its molecular… read more here.
Keywords: immunity infections; inflammation immunity; alpha macroglobulin;
Role of inflammation, immunity, and oxidative stress in hypertension: New insights and potential therapeutic targets
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1098725
Abstract: Hypertension is regarded as the most prominent risk factor for cardiovascular diseases, which have become a primary cause of death, and recent research has demonstrated that chronic inflammation is involved in the pathogenesis of hypertension.… read more here.
Keywords: inflammation; inflammation immunity; oxidative stress; hypertension ... See more keywords
The prognostic significance of inflammation-immunity-nutrition score on postoperative survival and recurrence in hepatocellular carcinoma patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.913731
Abstract: Background Inflammation, immunity, and nutrition status play important roles in tumorigenesis, progression, and metastasis. This study aimed to evaluate the prognostic value of Inflammation-Immunity-Nutrition Score (IINS) for overall survival (OS) and progression-free survival (PFS) in… read more here.
Keywords: inflammation immunity; immunity nutrition; iins afp; month auc ... See more keywords
A Review of Signaling Transduction Mechanisms in Osteoclastogenesis Regulation by Autophagy, Inflammation, and Immunity
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179846
Abstract: Osteoclastogenesis is an ongoing rigorous course that includes osteoclast precursors fusion and bone resorption executed by degradative enzymes. Osteoclastogenesis is controlled by endogenous signaling and/or regulators or affected by exogenous conditions and can also be… read more here.
Keywords: signaling transduction; inflammation immunity; autophagy inflammation; review signaling ... See more keywords