Butylphthalide ameliorates airway inflammation and mucus hypersecretion via NF-κB in a murine asthma model.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.105873
Abstract: Butylphthalide (NBP) is a phthalide compound contained in Angelicae Sinensis Radix which is one of the most widely used traditional Chinese medicines. This study aims to explore the therapeutic effect of NBP on airway inflammation,… read more here.
Keywords: mucus hypersecretion; airway inflammation; mucus; asthma model ... See more keywords
Monocyte chemotactic protein-inducing protein 1 negatively regulating asthmatic airway inflammation and mucus hypersecretion involving γ-aminobutyric acid type A receptor signaling pathway in vivo and in vitro
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000001154
Abstract: Abstract Background Mounting evidence, consistent with our previous study, showed that γ-aminobutyric acid type A receptor (GABAAR) played an indispensable role in airway inflammation and mucus hypersecretion in asthma. Monocyte chemotactic protein-inducing protein 1 (MCPIP1)… read more here.
Keywords: airway inflammation; inflammation mucus; inflammation; mucus hypersecretion ... See more keywords
Losartan reduces cigarette smoke-induced airway inflammation and mucus hypersecretion
Sign Up to like & getrecommendations! Published in 2020 at "ERJ Open Research"
DOI: 10.1183/23120541.00394-2020
Abstract: The aim was to determine whether losartan reduces cigarette smoke (CS)-induced airway inflammation and mucus hypersecretion in an in vitro model and a small clinical trial. Primary human bronchial epithelial cells (HBECs) were differentiated at… read more here.
Keywords: mucus hypersecretion; cigarette smoke; inflammation mucus; mucus ... See more keywords