Physalin A attenuates inflammation through down-regulating c-Jun NH2 kinase phosphorylation/Activator Protein 1 activation and up-regulating the antioxidant activity.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2020.115115
Abstract: Physalin A (PA), a withanolide, was isolated from Physalis angulata L. In this study, it is shown that PA can inhibit the production of inflammatory cytokines such as PGE2, NO, IL-1β, IL-6, and TNF-α in… read more here.
Keywords: physalin; regulating jun; physalin attenuates; attenuates inflammation ... See more keywords
β-Sitosterol inhibits ovalbumin-induced asthma-related inflammation by regulating dendritic cells
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DOI: 10.1080/08923973.2022.2102990
Abstract: Abstract Aim To investigate the effects of β-sitosterol (B-SIT) and the underlying mechanisms of action in an ovalbumin-induced rat model of asthma. Methods The pathological and morphological changes in lung and tracheal tissues were observed… read more here.
Keywords: sit; ovalbumin induced; regulating dendritic; inflammation regulating ... See more keywords
Butyrate suppresses atherosclerotic inflammation by regulating macrophages and polarization via GPR43/HDAC-miRNAs axis in ApoE−/− mice
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DOI: 10.1371/journal.pone.0282685
Abstract: Chronic low-grade inflammation is regarded to an important signature of atherosclerosis (AS). Macrophage (Mψ) and related polarization have been demonstrated to play a crucial role in the occurrence and development of AS inflammation. Butyrate, a… read more here.
Keywords: inflammation; atherosclerotic inflammation; inflammation regulating; butyrate ... See more keywords
Algal oil alleviates antibiotic-induced intestinal inflammation by regulating gut microbiota and repairing intestinal barrier
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DOI: 10.3389/fnut.2022.1081717
Abstract: Introduction Taking antibiotics would interfere with gut microbiota and increase the risk of opportunistic pathogen infection and inflammation. Methods In this study, 36 male C57BL/6 mice were divided into 4 groups (n = 9) to… read more here.
Keywords: gut microbiota; oil; inflammation regulating; algal oil ... See more keywords