Microheterogeneity and preanalytical stability of protein biomarkers of inflammation and renal function.
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DOI: 10.1016/j.talanta.2020.121774
Abstract: Protein biomarker microheterogeneity has attracted increasing attention in epidemiological and clinical research studies. Knowledge concerning the preanalytical stability of proteins is paramount to assess the biological significance of their proteoforms. We investigated the stability of… read more here.
Keywords: protein; preanalytical stability; inflammation renal; microheterogeneity ... See more keywords
Automated scoring of total inflammation in renal allograft biopsies
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DOI: 10.1111/ctr.14837
Abstract: Computer‐assisted scoring is gaining prominence in the evaluation of renal histology; however, much of the focus has been on identifying larger objects such as glomeruli. Total inflammation impacts graft outcome, and its quantification requires tools… read more here.
Keywords: inflammation; automated scoring; total inflammation; scoring total ... See more keywords
Ablation of Gadd45β ameliorates the inflammation and renal fibrosis caused by unilateral ureteral obstruction
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DOI: 10.1111/jcmm.15519
Abstract: The growth arrest and DNA damage‐inducible beta (Gadd45β) protein have been associated with various cellular functions, but its role in progressive renal disease is currently unknown. Here, we examined the effect of Gadd45β deletion on… read more here.
Keywords: ureteral obstruction; unilateral ureteral; gadd45; inflammation renal ... See more keywords
Microvascular Inflammation of the Renal Allograft: A Reappraisal of the Underlying Mechanisms
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DOI: 10.3389/fimmu.2022.864730
Abstract: Antibody-mediated rejection (ABMR) is associated with poor transplant outcomes and was identified as a leading cause of graft failure after kidney transplantation. Although the hallmark histological features of ABMR (ABMRh), i.e., microvascular inflammation (MVI), usually… read more here.
Keywords: inflammation; allograft reappraisal; hla dsas; microvascular inflammation ... See more keywords