Artificial Super Neutrophils for Inflammation Targeting and HClO Generation against Tumors and Infections.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201901179
Abstract: Neutrophils are powerful effector leukocytes that play an important role in innate immune systems for opposing tumor progression and ameliorating pathogen infections. Inspired by their distinct functions against tumors and infections, the artificial "super neutrophils"… read more here.
Keywords: super neutrophils; tumors infections; inflammation targeting; hclo generation ... See more keywords
Inflammation Targeting‐Triggered Healing Hydrogel for In Situ Reconstruction of Colonic Mucosa
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DOI: 10.1002/advs.202411010
Abstract: Inflammatory bowel disease (IBD) is characterized by intestinal mucosal damage that exacerbates inflammation and promotes disease recurrence. Although hydrogel‐based therapies have shown potential for mucosal repair, challenges remain due to inadequate targeting and low hydrogel… read more here.
Keywords: triggered healing; targeting triggered; hydrogel; inflammation ... See more keywords
miR-let-7a suppresses α-Synuclein-induced microglia inflammation through targeting STAT3 in Parkinson's disease.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.08.140
Abstract: Microglia-mediated neuroinflammation is critical for the pathogenesis of neurodegenerative diseases, including Parkinson's disease (PD). microRNA-let-7a (miR-let-7a) targets the signal transducer and activator of transcription-3 (STAT3) and regulates microglia function. However, less is known about whether… read more here.
Keywords: let suppresses; mir let; inflammation targeting; targeting stat3 ... See more keywords
Enhancing Inflammation Targeting Using Tunable Leukocyte-Based Biomimetic Nanoparticles
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DOI: 10.1021/acsnano.0c05792
Abstract: Biomimetic nanoparticles aim to effectively emulate the behavior of either cells or exosomes. Leukocyte-based biomimetic nanoparticles, for instance, incorporate cell membrane proteins to transfer the natural tropism of leukocytes to the final delivery platform. However,… read more here.
Keywords: leukocyte based; based biomimetic; inflammation targeting; enhancing inflammation ... See more keywords