The epidermal growth factor receptor inhibitor AG1478 inhibits eosinophilic inflammation in upper airways.
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DOI: 10.1016/j.clim.2017.11.010
Abstract: Mucus hypersecretion and eosinophil infiltration are important characteristics of eosinophilic inflammation in upper airways, such as allergic rhinitis and chronic rhinosinusitis with nasal polyp. EGFR transactivation induces mucus and inflammatory cytokine secretion from airway epithelial… read more here.
Keywords: inhibitor ag1478; inflammation upper; upper airways; eosinophilic inflammation ... See more keywords