A Programmed Anti-Inflammatory Nanoscaffold (PAIN) as a 3D Tool to Understand the Brain Injury Response.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced materials"
DOI: 10.1002/adma.201805209
Abstract: Immunology is the next frontier of nano/biomaterial science research, with the immune system determining the degree of tissue repair. However, the complexity of the inflammatory response represents a significant challenge that is essential to understand… read more here.
Keywords: anti inflammatory; response; inflammatory; programmed anti ... See more keywords
Engineered Extracellular Vesicles Derived from Dermal Fibroblasts Attenuate Inflammation in a Murine Model of Acute Lung Injury.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202210579
Abstract: Acute respiratory distress syndrome (ARDS) represents a significant burden to the health care system, with approximately 200,000 cases diagnosed annually in the US. ARDS patients suffer from severe refractory hypoxemia, alveolar-capillary barrier dysfunction, impaired surfactant… read more here.
Keywords: dermal fibroblasts; inflammation; engineered extracellular; lung ... See more keywords
Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202104372
Abstract: Recently, first insights into the regulation and the role of the RNA‐binding protein IMP2 in macrophage activation have been published by Wang et al. This study addresses differences in the regulation of IMP2 between the… read more here.
Keywords: inflammatory; reader igf2bp2; igf2bp2 regulates; m6a reader ... See more keywords
Inflammation‐Controlled Anti‐Inflammatory Hydrogels
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DOI: 10.1002/advs.202206412
Abstract: While autoregulative adaptation is a common feature of living tissues, only a few feedback‐controlled adaptive biomaterials are available so far. This paper herein reports a new polymer hydrogel platform designed to release anti‐inflammatory molecules in… read more here.
Keywords: controlled anti; anti inflammatory; inflammatory; inflammatory hydrogels ... See more keywords
All‐Natural Immunomodulatory Bioadhesive Hydrogel Promotes Angiogenesis and Diabetic Wound Healing by Regulating Macrophage Heterogeneity
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202206771
Abstract: Macrophages are highly heterogeneous and exhibit a diversity of functions and phenotypes. They can be divided into pro‐inflammatory macrophages (M1) and anti‐inflammatory macrophages (M2). Diabetic wounds are characterized by a prolonged inflammatory phase and difficulty… read more here.
Keywords: diabetic wound; inflammatory; wound healing; macrophage heterogeneity ... See more keywords
Some Novel Mannich Bases of 5‐(3,4‐Dichlorophenyl)‐1,3,4‐oxadiazole‐2(3H)‐one and Their Anti‐Inflammatory Activity
Sign Up to like & getrecommendations! Published in 2017 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.201700153
Abstract: Non‐steroidal anti‐inflammatory drugs (NSAIDs), which are widely used for the treatment of rheumatic arthritis, pain, and many different types of inflammatory disorders, cause serious gastrointestinal (GI) side effects. The free carboxylic acid group existing on… read more here.
Keywords: anti inflammatory; activity; mannich bases; inflammatory ... See more keywords
Anti‐inflammatory activity of pyridazinones: A review
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DOI: 10.1002/ardp.202200067
Abstract: The pyridazinone core has emerged as a leading structure for fighting inflammation, with low ulcerogenic effects. Moreover, easy functionalization of various ring positions of the pyridazinone core structure makes it an attractive synthetic and therapeutic… read more here.
Keywords: activity pyridazinones; anti inflammatory; inflammatory activity; inflammatory ... See more keywords
Effects of different physical training protocols on inflammatory markers in Zymosan‐induced rheumatoid arthritis in Wistar rats
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3697
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation and involvement of the synovial membrane, causing joint damage and deformities. No effective drug treatment is available, and physical exercise has been utilized to… read more here.
Keywords: zymosan induced; training; rheumatoid arthritis; inflammatory ... See more keywords
Multidrug Idebenone/Naproxen co-loaded Aspasomes for a Significant In VivoAnti-Inflammatory Activity.
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202200067
Abstract: The use of proper nanocarriers for dermal and transdermal delivery of anti-inflammatory drugs recently gained several attentions in the scientific community because they pass intact and accumulate payloads in the deepest layers of skin tissue.… read more here.
Keywords: idebenone naproxen; inflammatory; naproxen loaded; multidrug idebenone ... See more keywords
Imaging of translocator protein upregulation is selective for pro‐inflammatory polarized astrocytes and microglia
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DOI: 10.1002/glia.23716
Abstract: Translocator protein (TSPO) expression is increased in activated glia, and has been used as a marker of neuroinflammation in PET imaging. However, the extent to which TSPO upregulation reflects a pro‐ or anti‐inflammatory phenotype remains… read more here.
Keywords: astrocytes microglia; translocator protein; inflammatory; upregulation ... See more keywords
MicroRNA‐9a‐5p inhibits mucosal barrier injury in inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23131
Abstract: Our previous research found that FOXO1 aggravates the mucosal barrier injury in inflammatory bowel disease (IBD) by regulating TLR4/MD2 signaling. In this study, we further reveal the mechanism of action whereby miRNA‐9a‐5p inhibits the mucosal… read more here.
Keywords: mucosal barrier; barrier injury; disease; inflammatory ... See more keywords