Anti‐inflammatory activity of pyridazinones: A review
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200067
Abstract: The pyridazinone core has emerged as a leading structure for fighting inflammation, with low ulcerogenic effects. Moreover, easy functionalization of various ring positions of the pyridazinone core structure makes it an attractive synthetic and therapeutic… read more here.
Keywords: activity pyridazinones; anti inflammatory; inflammatory activity; inflammatory ... See more keywords
Diffusion kurtosis MRI versus conventional diffusion‐weighted imaging for evaluating inflammatory activity in Crohn's disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.25768
Abstract: To assess the efficacy of diffusion kurtosis imaging (DKI) and to compare DKI‐derived parameters with that of conventional diffusion‐weighted imaging (DWI) for grading the inflammatory activity of Crohn's disease (CD). read more here.
Keywords: diffusion; conventional diffusion; weighted imaging; inflammatory activity ... See more keywords
Formulated chitosan-sodium tripolyphosphate nanoparticles for co-encapsulation of ellagic acid and anti-inflammatory peptide: Characterization, stability and anti-inflammatory activity.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12521
Abstract: BACKGROUND The combined application of chitosan (CS) and tripolyphosphate (TPP) leads to the development of a suitable material with synergistic properties and promising potential for the conservation of food products. In this study, the ellagic… read more here.
Keywords: fpl nps; acid anti; anti inflammatory; inflammatory activity ... See more keywords
Phytosterols improve immunity and exert anti-inflammatory activity in weaned piglets.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.8277
Abstract: BACKGROUND Phytosterols (PS), plant-derived natural steroid compounds, are novel feed additives to regulate immune function and promote pig growth. This study was conducted to determine the effects of PS on the immune response of weaned… read more here.
Keywords: anti inflammatory; control; inflammatory activity; activity weaned ... See more keywords
Anti-inflammatory activity of β-caryophyllene combined with docosahexaenoic acid in a model of sepsis induced by Staphylococcus aureus in mice.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.9861
Abstract: BACKGROUND Sepsis is a set of serious organic manifestations caused by an infection, whose progression culminates in exacerbated inflammation and oxidative stress, poor prognosis, and high hospital costs. Antioxidants used against sepsis have been evaluated,… read more here.
Keywords: anti inflammatory; sepsis; docosahexaenoic acid; inflammatory activity ... See more keywords
Pharmacological Evaluation of Novel Organoiron Dendrimers as Antimicrobial and Anti-Inflammatory Agents.
Sign Up to like & getrecommendations! Published in 2020 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202000242
Abstract: The synthesis of a novel and attractive class of nonsteroidal anti-inflammatory and antimicrobial organoiron dendrimers attached to the well-known drug ibuprofen is achieved. The structures of these dendrimers are established by spectroscopic and analytical techniques.… read more here.
Keywords: anti inflammatory; inflammatory; inflammatory activity; organoiron dendrimers ... See more keywords
GREEN SYNTHESIS OF NEW SULFANYL DERIVATIVES OF AMPYRONE AND PREDICTION OF THEIR ANTI-INFLAMMATORY ACTIVITY
Sign Up to like & getrecommendations! Published in 2020 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/5472
Abstract: A selective method was developed for the synthesis of acyclic sulfanyl derivatives of ampyrone by thiomethylation reaction of 4-amino- 2,3-dimethyl-1-phenyl-3-pyrazolin-5-one with formaldehyde and thiols in aqueous medium under various conditions (room temperature, 80°C, ultrasonication or… read more here.
Keywords: derivatives ampyrone; anti inflammatory; sulfanyl derivatives; inflammatory activity ... See more keywords
Evaluating the inflammatory activity in Crohn’s disease using magnetic resonance diffusion kurtosis imaging
Sign Up to like & getrecommendations! Published in 2019 at "Abdominal Radiology"
DOI: 10.1007/s00261-019-02013-3
Abstract: ObjectivesTo explore the feasibility of diffusion kurtosis imaging (DKI) for evaluating inflammatory activity in Crohn’s disease (CD).Materials and methodsIn all, 51 CD patients were included, who were performed with consecutive enteroscopy, MR and DKI (b… read more here.
Keywords: inflammatory activity; activity; diffusion kurtosis; crohn disease ... See more keywords
NFL during acute spinal cord lesions in MS: a hurdle for the detection of inflammatory activity
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neurology"
DOI: 10.1007/s00415-021-10926-7
Abstract: Levels of neuro-filament light chain (NFL) correlate with clinical and radiological activity in multiple sclerosis (MS) and have been used as a surrogate biomarker of axonal destruction related to inflammatory activity. The main objective of… read more here.
Keywords: inflammatory activity; cord; spinal cord; nfl levels ... See more keywords
Oral 67Gallium Citrate Scintigraphy in assessment of inflammatory activity of Crohn’s disease: methodological issues on accuracy and agreement
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Nuclear Medicine"
DOI: 10.1007/s12149-020-01470-x
Abstract: I was interested to read the papers by Tajra JBM and colleagues entitled “Accuracy of Oral 67Gallium Citrate Scintigraphy in assessment of inflammatory activity of Crohn’s disease” published in Apr 2020 issue of Ann Nucl… read more here.
Keywords: inflammatory activity; agreement; crohn disease; scintigraphy ... See more keywords
Design, synthesis, analgesic, anti-inflammatory activity of novel pyrazolones possessing aminosulfonyl pharmacophore as inhibitors of COX-2/5-LOX enzymes: Histopathological and docking studies.
Sign Up to like & getrecommendations! Published in 2018 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.03.011
Abstract: A series of newly synthesized 4-aryl-hydrazonopyrazolones were designed and their structures were confirmed by spectral and elemental analyses. All synthesized compounds were evaluated for their in vitro COXs, 5-LOX inhibition, in vivo analgesic and anti-inflammatory… read more here.
Keywords: anti inflammatory; inflammatory activity; inflammatory; analgesic anti ... See more keywords