Protocatechuic acid reverses myocardial infarction mediated by β‐adrenergic agonist via regulation of Nrf2/HO‐1 pathway, inflammatory, apoptotic, and fibrotic events
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23270
Abstract: Myocardial infarction (MI) is an instant ischemic death of cardiomyocytes that remains a major global cause of mortalities. MI is accompanied by oxidative, inflammatory, apoptotic, and fibrotic insults. Protocatechuic acid (PCA) is a polyphenolic compound… read more here.
Keywords: apoptotic fibrotic; protocatechuic acid; inflammatory apoptotic; factor ... See more keywords
Heat acclimation increases inflammatory and apoptotic responses to subsequent LPS challenge in C2C12 myotubes
Sign Up to like & getrecommendations! Published in 2018 at "Cell Stress and Chaperones"
DOI: 10.1007/s12192-018-0923-0
Abstract: This work investigated the ability of a 6-day heat acclimation protocol to impart heat acclimation-mediated cross-tolerance (HACT) in C2C12 myotubes, as indicated by changes in inflammatory and apoptotic responses to subsequent lipopolysaccharide (LPS) challenge. Myotubes… read more here.
Keywords: apoptotic responses; heat acclimation; inflammatory apoptotic; lps ... See more keywords
Caffeic acid mitigates aflatoxin B1-mediated toxicity in the male rat reproductive system by modulating inflammatory and apoptotic responses, testicular function, and the redox-regulatory systems.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.14090
Abstract: Aflatoxin B1 (AFB1 ) is a toxic metabolite of public health concern. The present study investigates the protective effects of caffeic acid (CA) against AFB1 -induced oxidative stress, inflammation, and apoptosis in the hypothalamus, epididymis,… read more here.
Keywords: caffeic acid; male; rats coexposed; toxicity ... See more keywords
Empagliflozin Protects against Haloperidol Experimentally-Induced Ovarian Toxicity
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16020168
Abstract: The present experiment aimed to identify the potential protective role of empagliflozin (EMPA) on haloperidol (HAL)-induced ovarian damage in female rats because of its anti-inflammatory, antioxidant, and antiapoptotic effects. EMPA was administered in the presence… read more here.
Keywords: inflammatory apoptotic; oxidative stress; ovarian toxicity; group ... See more keywords