Inflammatory brain injury after severe viral infection is not unique to COVID-19
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DOI: 10.1093/brain/awac368
Abstract: This scientific commentary refers to ‘Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses’ by Needham et al. (https://doi.org/10.1093/brain/awac321). read more here.
Keywords: severe viral; brain; injury severe; brain injury ... See more keywords
Imaging of Childhood Inflammatory Brain Diseases
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DOI: 10.1097/rmr.0000000000000187
Abstract: Abstract Brain has been considered as an immune-privileged site for centuries owing to the presence of blood-brain barrier, absent lymphatic drainage, and antigen-presenting cells. However, the present prevailing concept is of immune surveillance where brain… read more here.
Keywords: imaging childhood; childhood inflammatory; inflammatory; inflammatory brain ... See more keywords
IL-33 modulates inflammatory brain injury but exacerbates systemic immunosuppression following ischemic stroke.
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DOI: 10.1172/jci.insight.121560
Abstract: Stroke triggers a complex inflammatory process in which the balance between pro- and antiinflammatory mediators is critical for the development of the brain infarct. However, systemic changes may also occur in parallel with brain inflammation.… read more here.
Keywords: ischemic stroke; inflammatory brain; brain injury; brain ... See more keywords
Simvastatin Upregulates Lipoxin A4 and Accelerates Neuroinflammation Resolution After Intracerebral Hemorrhage
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DOI: 10.2174/1567202619666220913124627
Abstract: Background Previous studies have demonstrated that statins can relieve inflammatory brain injury after intracerebral hemorrhage (ICH), but the mechanisms remain poorly characterized. This study aims to test whether simvastatin exerts an anti-inflammatory effect by regulating… read more here.
Keywords: brain; brain injury; inflammatory brain; intracerebral hemorrhage ... See more keywords
Microglial cathepsin B as a key driver of inflammatory brain diseases and brain aging
Sign Up to like & getrecommendations! Published in 2020 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.264444
Abstract: Interleukin-1β is a potent proinflammatory cytokine that plays a key role in the pathogenesis of the brain aging and diverse range of neurological diseases including Alzheimer’s disease, Parkinson’s disease, stroke and persistent pain. Activated microglia… read more here.
Keywords: diseases brain; cathepsin; inflammatory brain; brain diseases ... See more keywords