The influence of tissue antioxidant enzymes and inflammatory cascade in pathology of cystitis: An experimental rat model.
Sign Up to like & getrecommendations! Published in 2017 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2017.10.035
Abstract: We evaluate the role of antioxidant enzyme status and inflammatory cascade in disease progression of cystitis in a rat model. The animals were injected with clinically isolated Uropathogenic Escherichia coli (UPEC) and study the effect… read more here.
Keywords: inflammatory cascade; antioxidant enzymes; tissue; pathology ... See more keywords
Toll‐like receptor inflammatory cascade and the development of diabetic kidney disease in children and adolescents with type 1 diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Paediatrics and Child Health"
DOI: 10.1111/jpc.15884
Abstract: This study aimed to evaluate the association of toll‐like receptor (TLR) inflammatory cascade with the development of diabetic kidney disease (DKD) in children and adolescents with type 1 diabetes (T1D). read more here.
Keywords: toll like; cascade development; like receptor; inflammatory cascade ... See more keywords
Bioinspired catalytic nanogel as an inflammatory cascade-targeted therapeutic for rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-025-03642-1
Abstract: The inflammatory cascade is a key driver of chronic inflammation in rheumatoid arthritis (RA) and facilitates the migration of circulating immune cells into the inflamed joints. Recent studies have unveiled the complexity of this cascade,… read more here.
Keywords: inflammatory cascade; catalytic nanogel; inflammatory; rheumatoid arthritis ... See more keywords
AAV-mediated Overexpression of IL-10 Mitigates the Inflammatory Cascade in Stimulated Equine Chondrocyte Pellets.
Sign Up to like & getrecommendations! Published in 2018 at "Current gene therapy"
DOI: 10.2174/1566523218666180510165123
Abstract: BACKGROUND Following joint trauma, a posttraumatic inflammatory cascade drives degeneration of the joint. We aimed to assess whether transduction of chondrocytes with AAV5 overexpressing the immunomodulatory cytokine IL-10 would have protective effects in pellet cultures… read more here.
Keywords: chondrocyte pellets; overexpression; expression; inflammatory cascade ... See more keywords
Dynamic changes of enhancer and super enhancer landscape in degenerated nucleus pulposus cells
Sign Up to like & getrecommendations! Published in 2023 at "Life Science Alliance"
DOI: 10.26508/lsa.202201854
Abstract: Super-enhancers mediate inflammatory cascade and extracellular matrix remodeling in degenerated nucleus pulposus cells. Inflammatory cascade and extracellular matrix remodeling have been identified as pivotal pathological factors in the progression of intervertebral disc degeneration (IDD), but… read more here.
Keywords: extracellular matrix; inflammatory cascade; matrix remodeling; nucleus pulposus ... See more keywords