Oxaprozin prodrug as safer nonsteroidal anti‐inflammatory drug: Synthesis and pharmacological evaluation
Sign Up to like & getrecommendations! Published in 2018 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.201700256
Abstract: Oxaprozin is a popular non‐steroidal anti‐inflammatory drug (NSAID) and its chronic oral use is clinically restricted due to its gastrointestinal (GI) complications. In order to circumvent the GI complications, oxaprozin was amended as a prodrug… read more here.
Keywords: anti inflammatory; prodrug safer; inflammatory drug; prodrug ... See more keywords
Evaluating the effectiveness of nonsteroidal anti‐inflammatory drug(s) for relief of pain associated with temporomandibular joint disorders: A systematic review
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.241
Abstract: The aim of this systematic review was to compile the latest evidence to assess the effectiveness of nonsteroidal anti‐inflammatory drug(s) (NSAID) in patients with temporomandibular joint disorders (TMDs) in relieving pain. TMDs are a group… read more here.
Keywords: anti inflammatory; effectiveness nonsteroidal; systematic review; temporomandibular joint ... See more keywords
Flaming Mitochondria: The Anti-inflammatory Drug Leflunomide Boosts Mitofusins.
Sign Up to like & getrecommendations! Published in 2018 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2018.02.014
Abstract: Despite the significance of mitochondrial dynamics in many diseases, drugs that modulate it are lacking. In this issue of Cell Chemical Biology, Miret-Casals et al. (2018) use a phenotypic high-throughput screen to discover a pro-fusion role… read more here.
Keywords: anti inflammatory; drug leflunomide; drug; inflammatory drug ... See more keywords
Newly Synthesized 3-Indolyl Furanoid Inhibits Matrix Metalloproteinase-9 Activity and Prevents Nonsteroidal Anti-inflammatory Drug-Induced Gastric Ulceration.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.3c00511
Abstract: Indomethacin, a known nonsteroidal anti-inflammatory drug (NSAID) induces gastric inflammation, causing degradation of the extracellular matrix by specific matrix metalloproteinases (MMPs). We investigated the antiulcer efficacy of 3-indolyl furanoids (3g and 3c, i.e., methoxy substitution… read more here.
Keywords: nonsteroidal anti; anti inflammatory; activity; newly synthesized ... See more keywords
An investigation of the polymorphism of a potent nonsteroidal anti-inflammatory drug flunixin
Sign Up to like & getrecommendations! Published in 2020 at "CrystEngComm"
DOI: 10.1039/c9ce01619h
Abstract: Flunixin [2-(3-trifluoromethyl-2-methyl-phenylamino)-nicotinic acid, FLX], a potent nonsteroidal anti-inflammatory drug widely used in veterinary medicine, was found to exist in at least two crystal forms (I and II), in contrast to clonixin [2-(3-chloro-2-methyl-phenylamino)-nicotinic acid, CLX], which… read more here.
Keywords: anti inflammatory; potent nonsteroidal; nonsteroidal anti; inflammatory drug ... See more keywords
Relationship of Nonsteroidal Anti-Inflammatory Drug Use During Pregnancy with Autism Spectrum Disorder and Intellectual Disability Among Offspring.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of women's health"
DOI: 10.1089/jwh.2022.0113
Abstract: Objective: This study aimed to examine the association of nonsteroidal anti-inflammatory drug (NSAID) use by pregnant women during pregnancy with autism spectrum disorder (ASD) and intellectual disability (ID) in their children among Medicaid-insured mother-child dyads.… read more here.
Keywords: nonsteroidal anti; anti inflammatory; pregnancy; use pregnancy ... See more keywords
Inhibition of spinal 15-LOX-1 attenuates TLR4-dependent, nonsteroidal anti-inflammatory drug–unresponsive hyperalgesia in male rats
Sign Up to like & getrecommendations! Published in 2018 at "PAIN"
DOI: 10.1097/j.pain.0000000000001373
Abstract: Abstract Although nonsteroidal anti-inflammatory drugs are the first line of therapeutics for the treatment of mild to moderate somatic pain, they are not generally considered to be effective for neuropathic pain. In the current study,… read more here.
Keywords: anti inflammatory; drug unresponsive; nonsteroidal anti; inflammatory drug ... See more keywords
Determination of Non-Steroidal Anti-Inflammatory Drug (NSAID) Azathioprine in Human Blood Serum and Tablet Samples Using Multi-Walled Carbon Nanotubes (MWCNTs) Decorated Manganese Oxide Microcubes Composite Film Modified Electrode
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Electrochemical Science"
DOI: 10.20964/2017.08.145
Abstract: 1 Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, Taiwan 106 (ROC) 2 Graduate Institute of Biomedical and Biochemical Engineering, National Taipei University of Technology, Taipei, Taiwan 106 (ROC) 3 Research… read more here.
Keywords: anti inflammatory; steroidal anti; university; inflammatory drug ... See more keywords
Anti-Inflammatory Drug Therapy in Chronic Subdural Hematoma: A Systematic Review and Meta-Analysis of Prospective Randomized, Double-Blind and Placebo-Controlled Trials
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232416198
Abstract: Althoughanti-inflammatory drug therapy has been identified as potentially beneficial for patients suffering from chronic subdural hematoma (cSDH), contemporary literature presents contradictory results. In this meta-analysis, we aimed to investigate the impact of anti-inflammatory drug therapy… read more here.
Keywords: drug therapy; meta analysis; therapy; anti inflammatory ... See more keywords
Nonsteroidal Anti-Inflammatory Drug Conjugated with Gadolinium (III) Complex as an Anti-Inflammatory MRI Agent
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24076870
Abstract: Studies have been actively conducted to ensure that gadolinium-based contrast agents for magnetic resonance imaging (MRI) are accompanied by various biological functions. A new example is the anti-inflammatory theragnostic MRI agent to target inflammatory mediators… read more here.
Keywords: mri agent; nonsteroidal anti; anti inflammatory; mri ... See more keywords
Solubility Optimization of Loxoprofen as a Nonsteroidal Anti-Inflammatory Drug: Statistical Modeling and Optimization
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27144357
Abstract: Industrial-based application of supercritical CO2 (SCCO2) has emerged as a promising technology in numerous scientific fields due to offering brilliant advantages, such as simplicity of application, eco-friendliness, and high performance. Loxoprofen sodium (chemical formula C15H18O3)… read more here.
Keywords: nonsteroidal anti; solubility; anti inflammatory; inflammatory drug ... See more keywords