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Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23245
Abstract: We found that the expression of microRNA (miRNA)‐9a‐5p decreased in inflammatory bowel diseases (IBD; ulcerative colitis and Crohn's disease). Further, we revealed the effects and mechanisms of miRNA‐9a‐5p for regulating IBD progression. In C57BL/6N mice,…
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Keywords:
inhibits intestinal;
inflammatory injury;
microrna nox4;
intestinal inflammatory ... See more keywords
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Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.04.135
Abstract: Endothelial dysfunction plays an important role in the pathogenesis of acute lung injury (ALI). Tetramethylpyrazine (TMP) has been reported to attenuate harmful changes in ALI rats. However, the effects of TMP on endothelial cell injury…
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Keywords:
inflammatory injury;
lps group;
group;
huvecs ... See more keywords
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Published in 2019 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2019.01.056
Abstract: &NA; Osteoarthritis (OA) is a conversant joint disease, which seriously threatens the health of the elderly, and even leads to disability. Long non‐coding RNA‐activated by transforming growth factor beta (lncRNA‐ATB) has been reported in diverse…
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Keywords:
lncrna atb;
inflammatory injury;
atdc5 cells;
mir 223 ... See more keywords
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Published in 2019 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2019.02.014
Abstract: &NA; Kaempferol is a kind of bioflavonoid exerts diverse pharmacological activities, including anti‐apoptotic and anti‐inflammatory activities. Kaempferol has been recognized as an effective agent for alleviating the clinical symptoms of osteoarthritis (OA). This study aimed…
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Keywords:
atdc5 cells;
kaempferol;
mir 146a;
inflammatory injury ... See more keywords
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Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.04.004
Abstract: BACKGROUND Osteoarthritis (OA) is a familiar joint degenerative disease. Long non-coding RNAs (lncRNAs) play vital roles in the pathogenesis of OA. Nevertheless, the regulatory impacts of lncRNA highly up-regulated in liver cancer (lncRNA-HULC) on OA…
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Keywords:
hulc;
mir 101;
inflammatory injury;
atdc5 cells ... See more keywords
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Published in 2022 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2022.108759
Abstract: Cardiorenal syndrome (CRS) is the leading cause of death associated with chronic kidney disease (CKD) and end-stage renal disease (ESRD). However, the underlying mechanisms of CRS are still poorly understood. Here, we studied a CKD…
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Keywords:
cardiac fibrosis;
fibrosis;
inflammatory injury;
lymphangiogenesis ... See more keywords
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Published in 2020 at "Molecular immunology"
DOI: 10.1016/j.molimm.2020.04.013
Abstract: BACKGROUND Idebenone is a well-appreciated mitochondrial protectant while the mechanisms underlying the neuroprotection in cerebral ischemia and reperfusion (I/R) remain elusive. It has been manifested NLRP3 inflammasom activation contributed to I/R induced damage. It raises…
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Keywords:
ischemia reperfusion;
idebenone;
activation;
inflammatory injury ... See more keywords
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Published in 2021 at "PharmaNutrition"
DOI: 10.1016/j.phanu.2021.100278
Abstract: Abstract Background A poor-quality diet may contribute to chronic levels of inflammation and alter susceptibility to pain via activation of immune cells. Methods Here we examined the effect of a human-relevant Standard American Diet (SAD)…
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Keywords:
diet;
peripheral inflammatory;
standard american;
inflammatory injury ... See more keywords
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Published in 2022 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2022.2090954
Abstract: Abstract Background Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population and its pathogenesis has been associated with inflammatory damage to retinal pigment epithelial (RPE) cells. Here, we explored the…
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Keywords:
inflammatory injury;
sulforaphane;
induced inflammatory;
pwrn2 ... See more keywords
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Published in 2023 at "Stem Cells International"
DOI: 10.1155/2023/3328655
Abstract: Intestinal epithelial dysfunction is critical in the development of inflammatory bowel disease (IBD). However, most cellular experiments related to epithelial barrier studies in IBD have been based on tumor cell line that lack a variety…
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Keywords:
epithelial inflammatory;
inflammatory injury;
intestinal organoid;
model ... See more keywords
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Published in 2021 at "JCI Insight"
DOI: 10.1172/jci.insight.146089
Abstract: Macrophages are commonly thought to contribute to the pathophysiology of preterm labor by amplifying inflammation — but a protective role has not previously been considered to our knowledge. We hypothesized that given their antiinflammatory capability…
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Keywords:
inflammatory injury;
preterm birth;
fetal inflammatory;
birth ... See more keywords