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   Articles with "inflammatory injury" as a keyword



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MicroRNA‐9a‐5p‐NOX4 inhibits intestinal inflammatory injury by regulating the M1 polarization of intestinal macrophages

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recommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23245

Abstract: We found that the expression of microRNA (miRNA)‐9a‐5p decreased in inflammatory bowel diseases (IBD; ulcerative colitis and Crohn's disease). Further, we revealed the effects and mechanisms of miRNA‐9a‐5p for regulating IBD progression. In C57BL/6N mice,… read more here.

Keywords: inhibits intestinal; inflammatory injury; microrna nox4; intestinal inflammatory ... See more keywords
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Tetramethylpyrazine alleviates LPS-induced inflammatory injury in HUVECs by inhibiting Rho/ROCK pathway.

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recommendations! Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.04.135

Abstract: Endothelial dysfunction plays an important role in the pathogenesis of acute lung injury (ALI). Tetramethylpyrazine (TMP) has been reported to attenuate harmful changes in ALI rats. However, the effects of TMP on endothelial cell injury… read more here.

Keywords: inflammatory injury; lps group; group; huvecs ... See more keywords

Long non‐coding RNA activated by transforming growth factor beta alleviates lipopolysaccharide‐induced inflammatory injury via regulating microRNA‐223 in ATDC5 cells

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recommendations! Published in 2019 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2019.01.056

Abstract: &NA; Osteoarthritis (OA) is a conversant joint disease, which seriously threatens the health of the elderly, and even leads to disability. Long non‐coding RNA‐activated by transforming growth factor beta (lncRNA‐ATB) has been reported in diverse… read more here.

Keywords: lncrna atb; inflammatory injury; atdc5 cells; mir 223 ... See more keywords

Kaempferol protects chondrogenic ATDC5 cells against inflammatory injury triggered by lipopolysaccharide through down‐regulating miR‐146a

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recommendations! Published in 2019 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2019.02.014

Abstract: &NA; Kaempferol is a kind of bioflavonoid exerts diverse pharmacological activities, including anti‐apoptotic and anti‐inflammatory activities. Kaempferol has been recognized as an effective agent for alleviating the clinical symptoms of osteoarthritis (OA). This study aimed… read more here.

Keywords: atdc5 cells; kaempferol; mir 146a; inflammatory injury ... See more keywords

Long non-coding RNA highly up-regulated in liver cancer protects tumor necrosis factor-alpha-induced inflammatory injury by down-regulation of microRNA-101 in ATDC5 cells.

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recommendations! Published in 2019 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2019.04.004

Abstract: BACKGROUND Osteoarthritis (OA) is a familiar joint degenerative disease. Long non-coding RNAs (lncRNAs) play vital roles in the pathogenesis of OA. Nevertheless, the regulatory impacts of lncRNA highly up-regulated in liver cancer (lncRNA-HULC) on OA… read more here.

Keywords: hulc; mir 101; inflammatory injury; atdc5 cells ... See more keywords
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Eplerenone inhibits UUO-induced lymphangiogenesis and cardiac fibrosis by attenuating inflammatory injury.

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recommendations! Published in 2022 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2022.108759

Abstract: Cardiorenal syndrome (CRS) is the leading cause of death associated with chronic kidney disease (CKD) and end-stage renal disease (ESRD). However, the underlying mechanisms of CRS are still poorly understood. Here, we studied a CKD… read more here.

Keywords: cardiac fibrosis; fibrosis; inflammatory injury; lymphangiogenesis ... See more keywords
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Idebenone attenuates cerebral inflammatory injury in ischemia and reperfusion via dampening NLRP3 inflammasome activity.

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recommendations! Published in 2020 at "Molecular immunology"

DOI: 10.1016/j.molimm.2020.04.013

Abstract: BACKGROUND Idebenone is a well-appreciated mitochondrial protectant while the mechanisms underlying the neuroprotection in cerebral ischemia and reperfusion (I/R) remain elusive. It has been manifested NLRP3 inflammasom activation contributed to I/R induced damage. It raises… read more here.

Keywords: ischemia reperfusion; idebenone; activation; inflammatory injury ... See more keywords
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The effect of the Standard American Diet on Iba-1 immunoreactivity in the spinal cord before and after peripheral inflammatory injury in rats

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recommendations! Published in 2021 at "PharmaNutrition"

DOI: 10.1016/j.phanu.2021.100278

Abstract: Abstract Background A poor-quality diet may contribute to chronic levels of inflammation and alter susceptibility to pain via activation of immune cells. Methods Here we examined the effect of a human-relevant Standard American Diet (SAD)… read more here.

Keywords: diet; peripheral inflammatory; standard american; inflammatory injury ... See more keywords
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Sulforaphane alleviates LPS-induced inflammatory injury in ARPE-19 cells by repressing the PWRN2/NF-kB pathway

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recommendations! Published in 2022 at "Immunopharmacology and Immunotoxicology"

DOI: 10.1080/08923973.2022.2090954

Abstract: Abstract Background Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population and its pathogenesis has been associated with inflammatory damage to retinal pigment epithelial (RPE) cells. Here, we explored the… read more here.

Keywords: inflammatory injury; sulforaphane; induced inflammatory; pwrn2 ... See more keywords
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Establishment of Epithelial Inflammatory Injury Model Using Intestinal Organoid Cultures

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recommendations! Published in 2023 at "Stem Cells International"

DOI: 10.1155/2023/3328655

Abstract: Intestinal epithelial dysfunction is critical in the development of inflammatory bowel disease (IBD). However, most cellular experiments related to epithelial barrier studies in IBD have been based on tumor cell line that lack a variety… read more here.

Keywords: epithelial inflammatory; inflammatory injury; intestinal organoid; model ... See more keywords
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Macrophages exert homeostatic actions in pregnancy to protect against preterm birth and fetal inflammatory injury

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recommendations! Published in 2021 at "JCI Insight"

DOI: 10.1172/jci.insight.146089

Abstract: Macrophages are commonly thought to contribute to the pathophysiology of preterm labor by amplifying inflammation — but a protective role has not previously been considered to our knowledge. We hypothesized that given their antiinflammatory capability… read more here.

Keywords: inflammatory injury; preterm birth; fetal inflammatory; birth ... See more keywords