Development of a new calcilytic for the treatment of inflammatory lung disease
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.congress-2018.pa1060
Abstract: Background: Inhibitors of the extracellular calcium-sensing receptor (CaSR), termed calcilytics, were developed to evoke pulsatile changes in plasma parathyroid hormone (PTH) levels as a novel anti-osteoporotic treatment. Recently we have shown that they can suppress… read more here.
Keywords: inflammatory lung; new calcilytic; treatment inflammatory; treatment ... See more keywords
Inhaled simvastatin nanoparticles for inflammatory lung disease.
Sign Up to like & getrecommendations! Published in 2017 at "Nanomedicine"
DOI: 10.2217/nnm-2017-0188
Abstract: AIM Current inhaled treatments are not adequate to treat all lung diseases. In this study, a promising nanotechnology has been developed to deliver a potential anti-inflammatory and muco-inhibitory compound, simvastatin, for treatment of inflammatory lung… read more here.
Keywords: inflammatory lung; nanoparticles inflammatory; simvastatin nanoparticles; inhaled simvastatin ... See more keywords
Advances and opportunities in nanoimaging agents for the diagnosis of inflammatory lung diseases.
Sign Up to like & getrecommendations! Published in 2023 at "Nanomedicine"
DOI: 10.2217/nnm-2021-0427
Abstract: The development of rapid, noninvasive diagnostics to detect lung diseases is a great need after the COVID-2019 outbreak. The nanotechnology-based approach has improved imaging and facilitates the early diagnosis of inflammatory lung diseases. The multifunctional properties… read more here.
Keywords: lung; diagnosis inflammatory; lung diseases; inflammatory lung ... See more keywords
Nanotechnology-based therapeutics for targeting inflammatory lung diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Nanomedicine"
DOI: 10.2217/nnm-2021-0447
Abstract: The physiochemical properties of drugs used in treating inflammation-associated lung diseases (i.e., asthma, chronic obstructive pulmonary disease, pulmonary fibrosis) play an important role in determining the effectiveness of formulations. Most commonly used drugs are associated… read more here.
Keywords: nanotechnology; nanotechnology based; lung diseases; based therapeutics ... See more keywords
A new hope? Possibilities of therapeutic IgA antibodies in the treatment of inflammatory lung diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1127339
Abstract: Inflammatory lung diseases represent a persistent burden for patients and the global healthcare system. The combination of high morbidity, (partially) high mortality and limited innovations in the last decades, have resulted in a great demand… read more here.
Keywords: inflammatory lung; therapeutic iga; iga antibodies; lung diseases ... See more keywords
Astragalus polysaccharides alleviates lipopolysaccharides-induced inflammatory lung injury by altering intestinal microbiota in mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1033875
Abstract: Inflammatory lung injury is a common respiratory disease with limited therapeutic effects. Increasing opinions approved that prevention is more important than drug treatment for inflammatory lung injury. Astragalus polysaccharides (APS) has multiple bioactivities including anti-inflammation… read more here.
Keywords: inflammatory lung; injury; intestinal microbiota; lung injury ... See more keywords
Exosomal Non-Coding RNAs: Novel Regulators of Macrophage-Linked Intercellular Communication in Lung Cancer and Inflammatory Lung Diseases
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13030536
Abstract: Macrophages are innate immune cells and often classified as M1 macrophages (pro-inflammatory states) and M2 macrophages (anti-inflammatory states). Exosomes are cell-derived nanovesicles that range in diameter from 30 to 150 nm. Non-coding RNAs (ncRNAs), including… read more here.
Keywords: lung cancer; intercellular communication; lung; inflammatory lung ... See more keywords
Heparin, Low Molecular Weight Heparin, and Non-Anticoagulant Derivatives for the Treatment of Inflammatory Lung Disease
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DOI: 10.3390/ph16040584
Abstract: Unfractionated heparin has multiple pharmacological activities beyond anticoagulation. These anti-inflammatory, anti-microbial, and mucoactive activities are shared in part by low molecular weight and non-anticoagulant heparin derivatives. Anti-inflammatory activities include inhibition of chemokine activity and cytokine… read more here.
Keywords: non anticoagulant; molecular weight; lung disease; heparin ... See more keywords