Whole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in Chinese NSCLC patients
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-04492-2
Abstract: Chinese lung cancer patients have distinct epidemiologic and genomic features, highlighting the presence of specific etiologic mechanisms other than smoking. Here, we present a comprehensive genomic landscape of 149 non-small cell lung cancer (NSCLC) cases… read more here.
Keywords: associated inflammatory; nsclc patients; lung cancer; signatures associated ... See more keywords
Exosomes Represent an Immune Suppressive T Cell Checkpoint in Human Chronic Inflammatory Microenvironments
Sign Up to like & getrecommendations! Published in 2020 at "Immunological Investigations"
DOI: 10.1080/08820139.2020.1748047
Abstract: ABSTRACT Background: T cells present in chronic inflammatory tissues such as nasal polyps (from chronic rhinosinusitis patients) have been demonstrated to be hypo-responsive to activation via the TCR, similar to tumor-specific T cells in multiple… read more here.
Keywords: tumor; cell checkpoint; inflammatory; chronic inflammatory ... See more keywords