Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis.
Sign Up to like & getrecommendations! Published in 2021 at "Neurotoxicity research"
DOI: 10.1007/s12640-021-00417-y
Abstract: Multiple sclerosis (MS) is a chronic disorder characterized by reactive gliosis, inflammation, and demyelination. Microglia plays a crucial role in the pathogenesis of MS and has the dynamic plasticity to polarize between pro-inflammatory (M1) and… read more here.
Keywords: metformin therapy; metformin; inflammatory; pro inflammatory ... See more keywords
Abstract 36: Nanoparticulate Matter Exposure Causes a Time-Dependent Activation of Inflammatory Microglia With Associated White Matter Damage in a Mouse Model
Sign Up to like & getrecommendations! Published in 2020 at "Stroke"
DOI: 10.1161/str.51.suppl_1.36
Abstract: Introduction: Exposure to ambient air pollution, specifically the nano-scale subfraction (nPM; particles read more here.
Keywords: activation; matter damage; matter; inflammatory microglia ... See more keywords