Astragalus polysaccharide attenuates LPS‐related inflammatory osteolysis by suppressing osteoclastogenesis by reducing the MAPK signalling pathway
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16683
Abstract: Bacterial products can stimulate inflammatory reaction and activate immune cells to enhance the production of inflammatory cytokines, and finally promote osteoclasts recruitment and activity, leading to bone destruction. Unfortunately, effective preventive and treatment measures for… read more here.
Keywords: lps related; mapk signalling; inflammatory osteolysis; osteolysis ... See more keywords
Macrophage-biomimetic porous Se@SiO2 nanocomposites for dual modal immunotherapy against inflammatory osteolysis
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DOI: 10.1186/s12951-021-01128-4
Abstract: Background Inflammatory osteolysis, a major complication of total joint replacement surgery, can cause prosthesis failure and necessitate revision surgery. Macrophages are key effector immune cells in inflammatory responses, but excessive M1-polarization of dysfunctional macrophages leads… read more here.
Keywords: macrophage biomimetic; inflammatory osteolysis; osteolysis; biomimetic porous ... See more keywords
Ultrasmall PtAu2 nanoclusters activate endogenous anti-inflammatory and anti-oxidative systems to prevent inflammatory osteolysis
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DOI: 10.7150/thno.80514
Abstract: Rationale: Inflammatory osteolysis, characterized by abundant immune cell infiltration and osteoclast (OC) formation, is a common complication induced by bacterial products and/or wear particles at the bone-prosthesis interface that severely reduces long-term stability after implantation.… read more here.
Keywords: inflammatory osteolysis; osteolysis; inflammatory anti; anti inflammatory ... See more keywords