Cholinergic anti‐inflammatory pathway confers airway protection against oxidative damage and attenuates inflammation in an allergic asthma model
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29101
Abstract: Asthma is characterized by the influx of inflammatory cells, especially of eosinophils as well as reactive oxygen species (ROS) production, driven by the release of the T helper 2 (Th2)‐cell‐associated cytokines. The cholinergic anti‐inflammatory pathway… read more here.
Keywords: anti inflammatory; inflammation; inflammation allergic; inflammatory pathway ... See more keywords
Donepezil Prevents Inhibition of Cerebral Energetic Metabolism Without Altering Behavioral Parameters in Animal Model of Obesity
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemical Research"
DOI: 10.1007/s11064-020-03107-x
Abstract: Obesity is characterized by chronic inflammation of low grade. The cholinergic anti-inflammatory pathway favors the reduction of the inflammatory response. In this work the effect of stimulation of the cholinergic anti-inflammatory pathway on SHIRPA behavioral… read more here.
Keywords: anti inflammatory; donepezil; donepezil prevents; inflammatory pathway ... See more keywords
The cholinergic anti‐inflammatory pathway: an innovative treatment strategy for respiratory diseases and their comorbidities
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Pharmacology"
DOI: 10.1016/j.coph.2017.12.003
Abstract: HighlightsThe cholinergic anti‐inflammatory pathway modulates inflammatory responses.The &agr;7nAChR is the critical target on inflammatory cells in this pathway.Recent studies newly revealed neuron‐ILC2s interactions in allergic inflammation.Neuroimmune interactions are potential therapeutic targets for lung diseases. &NA;… read more here.
Keywords: anti inflammatory; cholinergic anti; inflammatory responses; inflammatory pathway ... See more keywords
Sevoflurane-induced inflammation development: involvement of cholinergic anti-inflammatory pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000507
Abstract: Chronic inflammation plays an important role in the mechanisms underpinning the development of anesthesia-induced cognitive dysfunction. However, less is known about how anesthesia causes inflammation. One possibility is that the inflammation is related to alteration… read more here.
Keywords: anti inflammatory; cholinergic anti; sevoflurane induced; inflammatory pathway ... See more keywords
Mechanism of inhibition of TLR4/NFκB/NLRP3 inflammatory pathway against AD based on the network pharmacology of Erjing Pills
Sign Up to like & getrecommendations! Published in 2024 at "Medicine"
DOI: 10.1097/md.0000000000039392
Abstract: Alzheimer disease is an irreversible neurodegenerative disease, and its pathogenesis involves various mechanisms such as neuroinflammation and β-amyloid deposition. Erjing Pills can inhibit neuroinflammation by inhibiting toll-like receptor 4/nuclear factor kappa-B/nucleotide-binding domain leucine-rich repeat and… read more here.
Keywords: erjing pills; pharmacology; network pharmacology; inflammatory pathway ... See more keywords
Photobiomodulation studies on diabetic wound healing: An insight into the inflammatory pathway in diabetic wound healing
Sign Up to like & getrecommendations! Published in 2024 at "Wound Repair and Regeneration"
DOI: 10.1111/wrr.13239
Abstract: Diabetes mellitus remains a global challenge to public health as it results in non‐healing chronic ulcers of the lower limb. These wounds are challenging to heal, and despite the different treatments available to improve healing,… read more here.
Keywords: diabetic wound; pathway diabetic; wound healing; inflammatory pathway ... See more keywords
Role of Cholinergic Anti-Inflammatory Pathway in Protecting Sepsis-Induced Acute Lung Injury through Regulation of the Conventional Dendritic Cells
Sign Up to like & getrecommendations! Published in 2022 at "Mediators of Inflammation"
DOI: 10.1155/2022/1474891
Abstract: Background The cholinergic anti-inflammatory pathway connects the immune response system and the nervous system via the vagus nerve. The key regulatory receptor is the α7-subtype of the nicotinic acetylcholine receptor (α7nAChR). Cholinergic anti-inflammatory pathway has… read more here.
Keywords: anti inflammatory; inflammatory pathway; conventional dcs; cholinergic anti ... See more keywords
Niloticin binds to MD-2 to promote anti-inflammatory pathway activation in macrophage cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/03946320221133017
Abstract: Objectives Niloticin is an active compound isolated from Cortex phellodendri with uncharacterized anti-inflammatory activity. We assessed the drug potential of niloticin and examined its ability to target myeloid differentiation protein 2 (MD-2) to ascertain the… read more here.
Keywords: inflammatory pathway; pharmacology; anti inflammatory; niloticin binds ... See more keywords
Inflammatory pathway communication with skeletal muscle—Does aging play a role? A topical review of the current evidence
Sign Up to like & getrecommendations! Published in 2024 at "Physiological Reports"
DOI: 10.14814/phy2.16098
Abstract: Skeletal muscle plays an integral role in locomotion, but also as part of the integrative physiological system. Recent progress has identified crosstalk between skeletal muscle and various physiological systems, including the immune system. Both the… read more here.
Keywords: skeletal muscle; pathway communication; role; muscle ... See more keywords
Homocysteine mediates transcriptional changes of the inflammatory pathway signature genes in human retinal pigment epithelial cells.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2017.05.06
Abstract: AIM To test whether homocysteine (Hcy) can influence the transcriptional profile, we hypothesized that Hcy can lead to the induction of proinflammatory molecules in the retinal cells of aging people. METHODS An unbiased in vitro… read more here.
Keywords: hcy; pigment epithelial; retinal cells; inflammatory pathway ... See more keywords
Alpha-ketoglutarate suppresses the NF-κB-mediated inflammatory pathway and enhances the PXR-regulated detoxification pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.16875
Abstract: Alpha-ketoglutarate (AKG) is a critical nutritional factor in the maintenance of intestinal homeostasis. However, the relative mechanism of AKG has not been well understood. It was recently shown that the interaction between nuclear factor kappa… read more here.
Keywords: alpha ketoglutarate; regulated detoxification; pxr regulated; pathway ... See more keywords