IL-37 blocks gouty inflammation by shaping macrophages into a non-inflammatory phagocytic phenotype.
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DOI: 10.1093/rheumatology/keac009
Abstract: OBJECTIVE Interleukin (IL)-37 is a natural suppressor of inflammation. Macrophages play an important role in acute gout flare by dominating the inflammation and spontaneous relief. We have reported IL-37 could limit runaway inflammation in gout.… read more here.
Keywords: inflammation; inflammatory phagocytic; gout; non inflammatory ... See more keywords