Oligoethyleneimine‐Conjugated Hyaluronic Acid Modulates Inflammatory Responses and Enhances Therapeutic Efficacy for Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202100548
Abstract: Modulation of innate immune responses is a potential strategy for treating inflammatory diseases. Although biogenic polyamines are known as immunomodulatory compounds possessing anti‐inflammatory functions, their biomedical applications have been limited owing to their cytotoxicity. Here,… read more here.
Keywords: therapeutic efficacy; hyaluronic acid; inflammatory responses; ulcerative colitis ... See more keywords
Multifunctional Antibacterial Nanonets Attenuate Inflammatory Responses Through Selective Trapping of Endotoxins and Pro-Inflammatory Cytokines.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203232
Abstract: Extracellular lipopolysaccharide (LPS) released from bacteria cells can enter the bloodstream and cause septic complications with excessive host inflammatory responses. Target-specific strategies to inactivate inflammation mediators have largely failed to improve the prognosis of septic… read more here.
Keywords: inflammatory responses; nanonets attenuate; multifunctional antibacterial; inflammatory cytokines ... See more keywords
Hybrid Biomaterial Initiates Refractory Wound Healing via Inducing Transiently Heightened Inflammatory Responses
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202105650
Abstract: Inflammation plays a crucial role in triggering regeneration, while inadequate or chronic inflammation hinders the regenerative process, resulting in refractory wounds. Inspired by the ideal regeneration mode in lower vertebrates and the human oral mucosa,… read more here.
Keywords: inflammation; inflammatory responses; transiently heightened; hybrid biomaterial ... See more keywords
Physiological pH Transition‐Driven Protein Corona Dynamics Regulate Cellular Uptake and Inflammatory Responses of Silica Nanoparticles
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202502788
Abstract: Protein corona alters the biological identities and interactions of nanoparticles with cells, needing to be thoroughly scrutinized before in vivo applications. Importantly, protein corona is evolving as nanoparticles cross different microenvironments, leading to unpredictable biological… read more here.
Keywords: protein corona; protein; inflammatory responses; corona dynamics ... See more keywords
Hibiscus schizopetalus boosts wound healing via restoring redox balance and hindering inflammatory responses in rats: Insights on metabolome profiling and molecular docking
Sign Up to like & getrecommendations! Published in 2024 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202400392
Abstract: Hibiscus species (Malvaceae) possess a plethora of appealing pharmacological activities with an extended history of customary use in diverse medical conditions. The present study aimed at comparing the metabolomic analyses of three Hibiscus species native… read more here.
Keywords: molecular docking; hse nanogel; wound healing; hibiscus ... See more keywords
Matrix Metalloproteinases 9 Contributes to Inflammatory Responses in Helicobacter pylori-Positive Gastric Cancer.
Sign Up to like & getrecommendations! Published in 2025 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.70000
Abstract: Helicobacter pylori-induced inflammatory microenvironment plays a pivotal role in the development of gastric cancer (GC). This study investigates whether matrix metallopeptidase 9 (MMP9) mediates H. pylori-induced effects in GC progression. GC patients were stratified on… read more here.
Keywords: mmp9; gastric cancer; pylori positive; helicobacter pylori ... See more keywords
Metformin inhibits pro‐inflammatory responses via targeting nuclear factor‐κB in HaCaT cells
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3367
Abstract: Psoriasis is a prevalent, chronic inflammatory skin disease that arises from rapid and excessive growth of keratinocytes induced by abnormal inflammatory responses. Metformin is the first‐line drug in type 2 diabetes and has been proven… read more here.
Keywords: inflammatory responses; metformin inhibits; hacat cells; factor ... See more keywords
Does habitat modification impact morphology, performance, and inflammatory responses in an amphibian with limited dispersal capacity (Lisssotriton helveticus)?
Sign Up to like & getrecommendations! Published in 2024 at "Ecology and Evolution"
DOI: 10.1002/ece3.70114
Abstract: Abstract The environment of an organism exerts selective pressures that affect mobility, feeding, reproduction as well as predator–prey and conspecific interactions. Land use changes induced by human activities modify these selective pressures and may result… read more here.
Keywords: morphology; selective pressures; performance; impact ... See more keywords
Rnf144b alleviates the inflammatory responses and cardiac dysfunction in sepsis.
Sign Up to like & getrecommendations! Published in 2023 at "ESC heart failure"
DOI: 10.1002/ehf2.14383
Abstract: AIMS Sepsis is an inflammatory disease with high mortality and morbidity. Inflammation plays an essential role in sepsis, and suppressing inflammation has been shown to ameliorate sepsis. Rnf144b is an ubiquitin E3 ligation with anti-inflammation… read more here.
Keywords: sepsis; rnf144b; inflammatory responses; responses cardiac ... See more keywords
TLR4 phosphorylation at tyrosine 672 activates the ERK/c-FOS signaling module for LPS-induced cytokine responses in macrophages.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250056
Abstract: Toll-like receptors (TLRs) engage numerous adaptor proteins and signaling molecules, enabling a complex series of post-translational modifications (PTMs) to mount inflammatory responses. TLRs themselves are post-translationally modified following ligand-induced activation, with this being required to… read more here.
Keywords: phosphorylation tyrosine; inflammatory responses; tyrosine 672; tlr4 phosphorylation ... See more keywords
Zerumin A attenuates the inflammatory responses in LPS‐stimulated H9c2 cardiomyoblasts
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22777
Abstract: Zerumin A (ZA) is one of the potential components of Curcuma amada rhizomes, and it has been shown to possess a variety of pharmacological activities. This study deals with the beneficial activity of ZA in… read more here.
Keywords: zerumin attenuates; inflammatory responses; responses lps; lps stimulated ... See more keywords