Oligoethyleneimine‐Conjugated Hyaluronic Acid Modulates Inflammatory Responses and Enhances Therapeutic Efficacy for Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202100548
Abstract: Modulation of innate immune responses is a potential strategy for treating inflammatory diseases. Although biogenic polyamines are known as immunomodulatory compounds possessing anti‐inflammatory functions, their biomedical applications have been limited owing to their cytotoxicity. Here,… read more here.
Keywords: therapeutic efficacy; hyaluronic acid; inflammatory responses; ulcerative colitis ... See more keywords
Multifunctional Antibacterial Nanonets Attenuate Inflammatory Responses Through Selective Trapping of Endotoxins and Pro-Inflammatory Cytokines.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203232
Abstract: Extracellular lipopolysaccharide (LPS) released from bacteria cells can enter the bloodstream and cause septic complications with excessive host inflammatory responses. Target-specific strategies to inactivate inflammation mediators have largely failed to improve the prognosis of septic… read more here.
Keywords: inflammatory responses; nanonets attenuate; multifunctional antibacterial; inflammatory cytokines ... See more keywords
Hybrid Biomaterial Initiates Refractory Wound Healing via Inducing Transiently Heightened Inflammatory Responses
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202105650
Abstract: Inflammation plays a crucial role in triggering regeneration, while inadequate or chronic inflammation hinders the regenerative process, resulting in refractory wounds. Inspired by the ideal regeneration mode in lower vertebrates and the human oral mucosa,… read more here.
Keywords: inflammation; inflammatory responses; transiently heightened; hybrid biomaterial ... See more keywords
Metformin inhibits pro‐inflammatory responses via targeting nuclear factor‐κB in HaCaT cells
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3367
Abstract: Psoriasis is a prevalent, chronic inflammatory skin disease that arises from rapid and excessive growth of keratinocytes induced by abnormal inflammatory responses. Metformin is the first‐line drug in type 2 diabetes and has been proven… read more here.
Keywords: inflammatory responses; metformin inhibits; hacat cells; factor ... See more keywords
Rnf144b alleviates the inflammatory responses and cardiac dysfunction in sepsis.
Sign Up to like & getrecommendations! Published in 2023 at "ESC heart failure"
DOI: 10.1002/ehf2.14383
Abstract: AIMS Sepsis is an inflammatory disease with high mortality and morbidity. Inflammation plays an essential role in sepsis, and suppressing inflammation has been shown to ameliorate sepsis. Rnf144b is an ubiquitin E3 ligation with anti-inflammation… read more here.
Keywords: sepsis; rnf144b; inflammatory responses; responses cardiac ... See more keywords
TLR4 phosphorylation at tyrosine 672 activates the ERK/c-FOS signaling module for LPS-induced cytokine responses in macrophages.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250056
Abstract: Toll-like receptors (TLRs) engage numerous adaptor proteins and signaling molecules, enabling a complex series of post-translational modifications (PTMs) to mount inflammatory responses. TLRs themselves are post-translationally modified following ligand-induced activation, with this being required to… read more here.
Keywords: phosphorylation tyrosine; inflammatory responses; tyrosine 672; tlr4 phosphorylation ... See more keywords
Zerumin A attenuates the inflammatory responses in LPS‐stimulated H9c2 cardiomyoblasts
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22777
Abstract: Zerumin A (ZA) is one of the potential components of Curcuma amada rhizomes, and it has been shown to possess a variety of pharmacological activities. This study deals with the beneficial activity of ZA in… read more here.
Keywords: zerumin attenuates; inflammatory responses; responses lps; lps stimulated ... See more keywords
Serum‐borne lipids amplify TLR‐activated inflammatory responses
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3ab0720-241rr
Abstract: TLRs recognize conserved pathogen associated molecular patterns and generate innate immune responses. Several circulating and cell membrane associated proteins have been shown to collaborate with TLRs in sensing microbial ligands and promoting inflammatory responses. Here,… read more here.
Keywords: serum borne; tlr activated; inflammatory responses; lipids amplify ... See more keywords
Impact of elexacaftor–tezacaftor–ivacaftor on bacterial colonization and inflammatory responses in cystic fibrosis
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DOI: 10.1002/ppul.26261
Abstract: Cystic fibrosis (CF) is a multisystem disease with progressive deterioration. Recently, CF transmembrane conductance regulator (CFTR) modulator therapies were introduced that repair underlying protein defects. Objective of this study was to determine the impact of… read more here.
Keywords: inflammatory responses; impact elexacaftor; elexacaftor tezacaftor; tezacaftor ivacaftor ... See more keywords
Lessons from dermatology about inflammatory responses in Covid‐19
Sign Up to like & getrecommendations! Published in 2020 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.2130
Abstract: The SARS‐Cov‐2 is a single‐stranded RNA virus composed of 16 non‐structural proteins (NSP 1‐16) with specific roles in the replication of coronaviruses. NSP3 has the property to block host innate immune response and to promote… read more here.
Keywords: responses covid; inflammatory responses; dermatology; dermatology inflammatory ... See more keywords
Protective effect of wogonin on inflammatory responses in BisGMA‐treated macrophages through the inhibition of MAPK and NFκB pathways
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23655
Abstract: Composites, resins, and sealants that are commonly used in orthopedics and dentistry are based on 2,2‐bis[p‐(2′‐hydroxy‐3′‐methacryloxypropoxy)phenylene]propane (BisGMA), which induces proinflammatory responses in macrophages. The present study aimed to explore the anti‐inflammatory responses of wogonin, which… read more here.
Keywords: inflammatory responses; treated macrophages; bisgma treated; phosphorylation ... See more keywords