Intracellular inflammatory signalling cascades in human monocytic cells on challenge with phytohemagglutinin and 2,4,6-trinitrophenol.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04296-x
Abstract: Phytohemagglutinin (PHA) is a plant mitogen that can agglutinate human leukocytes and erythrocytes. PHA is mainly derived from red kidney beans and can act as an exogenous pyrogen. When entering into the blood circulation, exogenous… read more here.
Keywords: inflammatory signalling; pha; inflammatory; pha tnp ... See more keywords
Aqueous extraction from dachengqi formula granules reduces the severity of mouse acute pancreatitis via inhibition of pancreatic pro-inflammatory signalling pathways.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.112861
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Dachengqi decoction (DCQD) belongs to a family of purgative herbal formulas widely used in China for the treatment of acute pancreatitis (AP). AP is a prevalent digestive disease currently without an effective pharmacological… read more here.
Keywords: inflammatory signalling; formula granules; severity; pancreatic pro ... See more keywords
Insulin-like growth factor-I activates NFκB and NLRP3 inflammatory signalling via ROS in cancer cells.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and cellular probes"
DOI: 10.1016/j.mcp.2020.101583
Abstract: Previous studies have demonstrated that insulin-like growth factor-I (IGF-1) and reactive oxygen species (ROS) are involved in the development and progression of various cancers. However, their regulatory mechanism remains unknown. In this study, we treated… read more here.
Keywords: activates nlrp3; inflammatory signalling; insulin like; cancer cells ... See more keywords
Drice restrains Diap2-mediated inflammatory signalling and intestinal inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Cell death and differentiation"
DOI: 10.1038/s41418-021-00832-w
Abstract: The Drosophila IAP protein, Diap2, is a key mediator of NF-κB signalling and innate immune responses. Diap2 is required for both local immune activation, taking place in the epithelial cells of the gut and trachea,… read more here.
Keywords: inflammatory signalling; drice; intestinal inflammation; immune responses ... See more keywords
The potential role of Bifidobacterium spp. as a preventive and therapeutic agent in controlling inflammation via affecting inflammatory signalling pathways
Sign Up to like & getrecommendations! Published in 2022 at "Letters in Applied Microbiology"
DOI: 10.1111/lam.13793
Abstract: Inflammatory bowel disease (IBD) is a chronic inflammatory disease with relapses and periods of remission. Forasmuch as, dysregulation of the immune system is one of the triggers of IBD, taking probiotics as one of the… read more here.
Keywords: inflammation; bifidobacterium spp; inflammatory signalling; bifidobacterium ... See more keywords
Role of self-organising myddosome oligomers in inflammatory signalling by Toll-like receptors
Sign Up to like & getrecommendations! Published in 2019 at "BMC Biology"
DOI: 10.1186/s12915-019-0637-5
Abstract: A paper published in BMC Biology characterises biophysically oligomeric and filamentous structures formed spontaneously by the Toll-like receptor signalling adaptor MyD88. Naturally occurring mutants of MyD88 that cause immunodeficiency are unable to form these structures.… read more here.
Keywords: self organising; toll like; inflammatory signalling; organising myddosome ... See more keywords
Pro-Inflammatory Signalling PRRopels Cisplatin-Induced Toxicity
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137227
Abstract: Cisplatin is a platinum-based chemotherapeutic that has long since been effective against a variety of solid-cancers, substantially improving the five-year survival rates for cancer patients. Its use has also historically been limited by its adverse… read more here.
Keywords: inflammatory signalling; pro inflammatory; cisplatin induced; cisplatin ... See more keywords