Pharmacokinetic Similarity of ABP 710, a Proposed Biosimilar to Infliximab: Results From a Randomized, Single‐Blind, Single‐Dose, Parallel‐Group Study in Healthy Subjects
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.738
Abstract: This was a randomized, single‐blind, single‐dose, 3‐arm parallel‐group study. Healthy subjects were randomized to receive ABP 710 (n = 50) or infliximab reference product (RP) sourced from the United States (infliximab US; n = 50)… read more here.
Keywords: infliximab; 710 infliximab; similarity abp; abp 710 ... See more keywords
Improvement in disease activity among patients with rheumatoid arthritis who switched from intravenous infliximab to intravenous golimumab in the ACR RISE registry
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DOI: 10.1007/s10067-022-06116-z
Abstract: Infliximab and golimumab are intravenously (IV) administered tumor necrosis factor inhibitors approved to treat moderate-to-severe rheumatoid arthritis (RA) with concomitant methotrexate. Owing to differences in biologic construct, patients with IV-infliximab treatment failure may benefit from… read more here.
Keywords: rheumatoid arthritis; infliximab; disease; disease activity ... See more keywords
Two Strikes but Not Out: Deep Remission of Ulcerative Colitis with Ustekinumab After Primary Non-response to Infliximab and Vedolizumab
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DOI: 10.1007/s10620-021-06852-3
Abstract: A 27-year-old female with a history of hypertension was diagnosed with pan-ulcerative colitis (UC) after experiencing several weeks of diarrhea, hematochezia, and abdominal cramping. She was initially treated with 5-ASA and azathioprine, both of which… read more here.
Keywords: vedolizumab; infliximab; colitis; ulcerative colitis ... See more keywords
Analytical and Functional Similarity Assessment of ABP 710, a Biosimilar to Infliximab Reference Product
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DOI: 10.1007/s11095-020-02816-w
Abstract: Purpose ABP 710 has been developed as a biosimilar to infliximab reference product (RP). The objective of this study was to assess analytical similarity (structural and functional) between ABP 710 and infliximab RP licensed by… read more here.
Keywords: infliximab reference; similarity; infliximab; biosimilar infliximab ... See more keywords
As Infliximab Use for Ulcerative Colitis Has Increased, so Has the Rate of Surgical Resection
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DOI: 10.1007/s11605-017-3431-0
Abstract: BackgroundInfliximab was approved for ulcerative colitis in 2005 after randomized trials showed it reduced the risk of colectomy. Its effect on population-level surgery rates is unknown. Our aim is to assess the impact of infliximab… read more here.
Keywords: surgical resection; surgery; infliximab; colitis ... See more keywords
Evaluation of the Effects of Biological Therapy with Infliximab in an Experimental Model of Diversion Colitis
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DOI: 10.1007/s11605-021-04981-8
Abstract: Diversion colitis (DC) is an inflammatory disease that occurs in colonic segments without fecal stream (WFS). 1 The lack of supply of short-chain fatty acids (SCFAs) to the cells of mucosa WFS causes changes in… read more here.
Keywords: diversion; infliximab; diversion colitis; effects biological ... See more keywords
The efficacy of infliximab combined with surgical treatment of fistulizing perianal Crohn's disease: Comparative analysis according to fistula subtypes.
Sign Up to like & getrecommendations! Published in 2018 at "Asian journal of surgery"
DOI: 10.1016/j.asjsur.2017.06.005
Abstract: BACKGROUND/OBJECTIVE Infliximab is regarded as an effective therapeutic to treat Crohn's disease. This study aimed to assess the efficacy of infliximab combined with surgery and to analyze clinical manifestations according to fistula subtypes in patients… read more here.
Keywords: response; infliximab; disease; perianal crohn ... See more keywords
Taponamiento cardíaco. Una complicación del tratamiento con infliximab
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DOI: 10.1016/j.medcli.2017.03.015
Abstract: Infliximab es un anticuerpo monoclonal anti-TNFque se tiliza en el tratamiento de la artritis reumatoide, la espondiliis anquilosante, la artritis psoriásica y la enfermedad de Crohn. a pericarditis ha sido descrita como una reacción adversa… read more here.
Keywords: del tratamiento; con; infliximab; tratamiento con ... See more keywords
Idiopathic Retinal Vasculitis, Aneurysms and Neuroretinitis: Clinical Improvement with Infliximab
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DOI: 10.1080/09273948.2022.2027466
Abstract: ABSTRACT Purpose Idiopathic retinal vasculitis, aneurysms and neuroretinitis is a rare vision-threatening condition. If untreated vision loss occurs due to complications of progressive retinal ischaemia including retinal neovascularisation, neovascular glaucoma and retinal exudation. Despite the… read more here.
Keywords: vasculitis; retinal vasculitis; aneurysms neuroretinitis; infliximab ... See more keywords
The efficacy of systemic and intravitreal infliximab treatments in an endotoxin-induced uveitis model
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DOI: 10.1080/15569527.2019.1632883
Abstract: Abstract Purpose: To compare the efficacy of systemic and intravitreal infliximab treatments in an experimental endotoxin-induced uveitis (EIU) model. Methods: Twenty-eight white New Zealand rabbits were equally divided into 4 groups. Group 1 received an… read more here.
Keywords: intravitreal infliximab; infliximab; group; model ... See more keywords
The first World Health Organization International Standard for infliximab products: A step towards maintaining harmonized biological activity
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DOI: 10.1080/19420862.2018.1532766
Abstract: ABSTRACT Due to the increase in the number of infliximab products, the need for global harmonization of the bioactivity of this monoclonal antibody was recognized by the World Health Organization (WHO). In response, the National… read more here.
Keywords: infliximab products; infliximab; health organization; world health ... See more keywords