Delayed cutaneous hypersensitivity reactions following the use of infliximab or adalimumab in patients with coronavirus disease 2019
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28518
Abstract: Recent evidence has emerged concerning delayed cutaneous hypersensitivity reactions after infliximab or adalimumab applications in patients with coronavirus disease 2019 (COVID‐19). A few real‐world studies compared the events, clinical features, and prognosis of infliximab‐ or… read more here.
Keywords: infliximab adalimumab; cutaneous hypersensitivity; hypersensitivity reactions; delayed cutaneous ... See more keywords
MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Genomics"
DOI: 10.1016/j.ygeno.2021.04.011
Abstract: Infliximab/adalimumab (IFX/ADA) and vedolizumab (VDZ) are the most widely used biologics in inflammatory bowel diseases. Current models used to predict their efficacies are restricted to either Crohn's disease or ulcerative colitis or to only one… read more here.
Keywords: ifx ada; vdz; inflammatory bowel; bowel diseases ... See more keywords
Effect of Infliximab and Adalimumab on Experimental Colitis Following Orally Supplemented Iron
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Investigative Surgery"
DOI: 10.1080/08941939.2016.1215574
Abstract: ABSTRACT Background: Orally administered iron can induce colonic inflammation in healthy animals and aggravate experimental colitis. Aim: To investigate the influence of the biologic agents infliximab and adalimumab on the severity of TNBS colitis following… read more here.
Keywords: following orally; colitis; colitis following; infliximab adalimumab ... See more keywords
Immunogenicity of infliximab and adalimumab
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2019.1602117
Abstract: TNF-α inhibitors have demonstrated efficacy both as monotherapy and in combination with disease-modifying anti-rheumatic drugs (DMARDs) in the treatment of chronic inflammatory immune-mediated diseases [1,2]. TNF-α may promote progression of endothelial dysfunction and, thus, of… read more here.
Keywords: immunogenicity infliximab; infliximab adalimumab;
Validation Study of a New Random-Access Chemiluminescence Immunoassay Analyzer i-TRACK10® to Monitor Infliximab and Adalimumab Serum trough Levels and Anti-Drug Antibodies
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179561
Abstract: Background. Monitoring of biological TNF inhibitors is a very important tool to guide clinical decisions using specialized algorithms, especially in gastroenterology. A new chemiluminescent instrument (i-TRACK10® from Theradiag) could replace ELISA techniques to calculate the… read more here.
Keywords: drug antibodies; anti drug; random access; new random ... See more keywords
Optimising the Therapeutic Interval for Biologics in Patients with Psoriasis
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12122075
Abstract: In our clinical experience, more than half of patients do not present a complete response to biologic drugs, or drug loses its efficacy over time. Plasma determinations of drug and anti-drug antibodies levels are an… read more here.
Keywords: therapeutic ranges; optimising therapeutic; therapeutic interval; study ... See more keywords
Higher infliximab and adalimumab trough levels are associated with fistula healing in patients with fistulising perianal Crohn’s disease
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v28.i23.2597
Abstract: BACKGROUND Tumor necrosis factor-alpha inhibitors, including infliximab and adalimumab, are effective medical treatments for perianal fistulising Crohn’s disease (CD), but not all patients achieve fistula healing. AIM To determine the correlation between perianal fistula healing… read more here.
Keywords: adalimumab trough; trough levels; infliximab adalimumab; fistula healing ... See more keywords
Quantification of infliximab and adalimumab in human plasma by a liquid chromatography tandem mass spectrometry kit and comparison with two ELISA methods.
Sign Up to like & getrecommendations! Published in 2022 at "Bioanalysis"
DOI: 10.4155/bio-2022-0057
Abstract: Background: This study compared the performance of plasma infliximab and adalimumab quantification using a commercially available kit (mAbXmise kit) and mass spectrometry readout to that of two ELISA methods in patients treated for inflammatory bowel disease.… read more here.
Keywords: mass spectrometry; elisa methods; infliximab adalimumab; two elisa ... See more keywords