Infliximab induces clinical resolution of sacroiliitis that coincides with increased circulating FOXP3+ T cells in a patient with IPEX syndrome.
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DOI: 10.1016/j.jbspin.2020.04.013
Abstract: Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a rare monogenic primary immunodeficiency due to mutations of FOXP3, a master transcription factor of regulatory T cells (Treg). IPEX syndrome leads to fatal course in most… read more here.
Keywords: infliximab induces; resolution; sacroiliitis; circulating foxp3 ... See more keywords