The Influence of the CES1 Genotype on the Pharmacokinetics of Enalapril in Patients with Arterial Hypertension
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DOI: 10.3390/jpm12040580
Abstract: The angiotensin-converting enzyme inhibitor enalapril is hydrolysed to an active metabolite, enalaprilat, in the liver via carboxylesterase 1 (CES1). Previous studies show that variant rs71647871 in the CES1 gene affects the pharmacokinetics of enalapril on… read more here.
Keywords: arterial hypertension; patients arterial; pharmacokinetics enalapril; influence ces1 ... See more keywords