Influence of Fc Modifications and IgG Subclass on Biodistribution of Humanized Antibodies Targeting L1CAM
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DOI: 10.2967/jnumed.121.262383
Abstract: Visual Abstract Immuno-PET is a powerful tool to noninvasively characterize the in vivo biodistribution of engineered antibodies. Methods: L1 cell adhesion molecule–targeting humanized (HuE71) IgG1 and IgG4 antibodies bearing identical variable heavy- and light-chain sequences… read more here.
Keywords: biodistribution; influence modifications; hue71 igg1; igg subclass ... See more keywords