A Buried Water Molecule Influences Reactivity in α-Amylase on a Subnanosecond Time Scale
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DOI: 10.1021/acscatal.7b04400
Abstract: The subset of catalytically competent conformations can be significantly small in comparison with the full conformational landscape of enzyme–substrate complexes. In some enzymes, the probability of finding a reactive conformation can account for up to… read more here.
Keywords: water molecule; buried water; influences reactivity; molecule influences ... See more keywords