Co-circulation of multiple genotypes of influenza A (H7N9) viruses in eastern China, 2016-2017
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DOI: 10.1007/s00705-018-3800-3
Abstract: Five epidemic waves of human infection with influenza A (H7N9) virus have emerged in China since spring 2013. We previously described the epidemiological characterization of the fifth wave in Jiangsu province. In this study, 41… read more here.
Keywords: fifth wave; influenza h7n9; multiple genotypes; h7n9 ... See more keywords
Amino Acid Substitutions N123D and N149D in Hemagglutinin Molecule Enhance Immunigenicity of Live Attenuated Influenza H7N9 Vaccine Strain in Experiment
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DOI: 10.1007/s10517-019-04407-1
Abstract: We compared three cold-adapted live attenuated influenza vaccine strains prepared by reverse genetics methods on the basis of master donor virus A/Leningrad/134/17/57 and influenza H7N9 strains A/Anhui/1/2013 and A/Shanghai/1/2013. Two strains based on A/Anhui/1/2013 differed… read more here.
Keywords: anhui 2013; influenza h7n9; attenuated influenza; live attenuated ... See more keywords
A Gene Constellation in Avian Influenza A (H7N9) Viruses May Have Facilitated the Fifth Wave Outbreak in China.
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DOI: 10.1016/j.celrep.2018.03.081
Abstract: The 2016-2017 epidemic of influenza A (H7N9) virus in China prompted concern that a genetic change may underlie increased virulence. Based on an evolutionary analysis of H7N9 viruses from all five outbreak waves, we find… read more here.
Keywords: influenza h7n9; wave; h7n9; constellation ... See more keywords
Safety and immunogenicity of an 8 year interval heterologous prime-boost influenza A/H7N7-H7N9 vaccination.
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DOI: 10.1016/j.vaccine.2019.03.071
Abstract: BACKGROUND Influenza A/H7N9 viruses are undergoing antigenic drift since their emergence in 2013, and vaccination strategies are needed for pandemic preparedness. Two doses of adjuvanted monovalent inactivated influenza A/H7N9 vaccine (IIV1 A/H7N9) are needed for… read more here.
Keywords: h7n9; iiv1 h7n9; influenza h7n9; prime boost ... See more keywords
The PB2 mutation with lysine at 627 enhances the pathogenicity of avian influenza (H7N9) virus which belongs to a non-zoonotic lineage
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DOI: 10.1038/s41598-017-02598-z
Abstract: A novel avian-origin influenza A (H7N9) virus emerged in China in 2013 and has caused zoonotic disease in over 1123 persons with an overall mortality around 30%. Amino acid changes at the residues 591, 627… read more here.
Keywords: h7n9 virus; influenza h7n9; lineage; h7n9 ... See more keywords
Adaptation of influenza A (H7N9) virus in primary human airway epithelial cells
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DOI: 10.1038/s41598-017-10749-5
Abstract: Influenza A (H7N9) is an emerging zoonotic pathogen with pandemic potential. To understand its adaptation capability, we examined the genetic changes and cellular responses following serial infections of A (H7N9) in primary human airway epithelial… read more here.
Keywords: primary human; h7n9 virus; human airway; influenza h7n9 ... See more keywords
Long term outcomes in survivors of epidemic Influenza A (H7N9) virus infection
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DOI: 10.1038/s41598-017-17497-6
Abstract: Patients who survive influenza A (H7N9) virus infection are at risk of physical and psychological complications of lung injury and multi-organ dysfunction. However, there were no prospectively individualized assessments of physiological, functional and quality-of-life measures… read more here.
Keywords: h7n9 virus; influenza h7n9; long term; h7n9 ... See more keywords
Benefit of Early Initiation of Neuraminidase Inhibitor Treatment to Hospitalized Patients With Avian Influenza A(H7N9) Virus
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DOI: 10.1093/cid/cix930
Abstract: Background The significance of early neuraminidase inhibitor (NAI) therapy for treating influenza A(H7N9) is currently unknown. Methods The duration of viral shedding was monitored by reverse-transcription polymerase chain reaction after patients with confirmed H7N9 infection… read more here.
Keywords: viral shedding; within days; influenza h7n9; nai therapy ... See more keywords
Avian Influenza A (H7N9) Model Based on Poultry Transport Network in China
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DOI: 10.1155/2018/7383170
Abstract: In order to analyze the spread of avian influenza A (H7N9), we construct an avian influenza transmission model from poultry (including poultry farm, backyard poultry farm, live-poultry wholesale market, and wet market) to human according… read more here.
Keywords: poultry transport; avian influenza; influenza h7n9; poultry ... See more keywords
Erratum to: Population seroprevalence of antibody to influenza A(H7N9) virus, Guangzhou, China
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DOI: 10.1186/s12879-017-2359-z
Abstract: Background: Since the identification in early 2013 of severe disease caused by influenza A(H7N9) virus infection, there have been few attempts to characterize the full severity profile of human infections. Our objective was to estimate… read more here.
Keywords: h7n9 virus; influenza h7n9; antibody; virus ... See more keywords
Increase in Human Infections with Avian Influenza A(H7N9) Virus During the Fifth Epidemic — China, October 2016–February 2017
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DOI: 10.15585/mmwr.mm6609e2
Abstract: During March 2013-February 24, 2017, annual epidemics of avian influenza A(H7N9) in China resulted in 1,258 avian influenza A(H7N9) virus infections in humans being reported to the World Health Organization (WHO) by the National Health… read more here.
Keywords: avian influenza; h7n9 virus; influenza h7n9; h7n9 ... See more keywords