Microwave-assisted synthesis, characterization and bioassay of acylhydrazone derivatives as influenza neuraminidase inhibitors
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DOI: 10.1007/s00044-017-2015-6
Abstract: A series of acylhydrazone derivatives (4a–4s) were synthesized via microwave irradiation with short reaction time and good yields. The crystal structure of compound 4j was further determined by single-crystal X-ray diffraction. All of the derivatives… read more here.
Keywords: microwave assisted; assisted synthesis; neuraminidase inhibitors; influenza neuraminidase ... See more keywords
Assessment of adverse events related to anti-influenza neuraminidase inhibitors using the FDA adverse event reporting system and online patient reviews
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DOI: 10.1038/s41598-020-60068-5
Abstract: The recommended antiviral drugs available for the treatment and prevention of influenza are neuraminidase inhibitors (NAIs). The aim of this study was to evaluate age-related clinical manifestations of adverse events (AEs) related to NAIs. FAERS… read more here.
Keywords: reporting; adverse events; assessment adverse; influenza neuraminidase ... See more keywords
DNA-linked inhibitor antibody assay (DIANA) as a new method for screening influenza neuraminidase inhibitors.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Journal"
DOI: 10.2210/pdb6g01/pdb
Abstract: Influenza neuraminidase is responsible for the escape of new viral particles from the infected cell surface. Several neuraminidase inhibitors are used clinically to treat patients or stockpiled for emergencies. However, the increasing development of viral… read more here.
Keywords: neuraminidase; inhibitor; antibody; method ... See more keywords