Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition
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DOI: 10.1038/s41467-018-04214-8
Abstract: RIG-I is a viral RNA sensor that induces the production of type I interferon (IFN) in response to infection with a variety of viruses. Modification of RIG-I with K63-linked poly-ubiquitin chains, synthesised by TRIM25, is… read more here.
Keywords: trim25; influenza; recognition; molecular mechanism ... See more keywords
Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins
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DOI: 10.3390/v10120708
Abstract: Influenza A viruses (IAV) can infect a broad range of animal hosts, including humans. In humans, IAV causes seasonal annual epidemics and occasional pandemics, representing a serious public health and economic problem, which is most… read more here.
Keywords: ns1 proteins; immune responses; host; innate immune ... See more keywords