Comparison of mucosal lining fluid sampling methods and influenza-specific IgA detection assays for use in human studies of influenza immunity.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2017.06.008
Abstract: We need greater understanding of the mechanisms underlying protection against influenza virus to develop more effective vaccines. To do this, we need better, more reproducible methods of sampling the nasal mucosa. The aim of the… read more here.
Keywords: sampling methods; specific iga; iga; mucosal ... See more keywords
Penalized Supervised Star Plots: Example Application in Influenza-Specific CD4+ T Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Viral immunology"
DOI: 10.1089/vim.2018.0046
Abstract: An immune cell's phenotype expresses through its high-dimensional marker signature. Cluster analyses of data from high-throughput mass and flow cytometry marker panels permit discovery of previously undescribed immune cell phenotypes. Impactful reporting of new phenotypes… read more here.
Keywords: supervised star; penalized supervised; star plots; influenza specific ... See more keywords
Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity
Sign Up to like & getrecommendations! Published in 2018 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aan8405
Abstract: Analysis of influenza-specific B cells during antigen exposure and tissue compartmentalization provides insights into human B cell memory. Investigating influenza immunity Seasonal influenza vaccines have been recommended for decades, but studies focused on antigen-specific lymphocytes… read more here.
Keywords: immunity; tfh cells; influenza specific; cell ... See more keywords
Harmonization and qualification of intracellular cytokine staining to measure influenza-specific CD4+ T cell immunity within the FLUCOP consortium
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.982887
Abstract: Despite the knowledge that cell-mediated immunity (CMI) contributes to the reduction of severe influenza infection, transmission, and disease outcome, the correlates of protection for cell-mediated immunity remain still unclear. Therefore, measuring the magnitude and quality… read more here.
Keywords: cell; influenza specific; cd4; immunity ... See more keywords
Harmonization and qualification of an IFN-γ Enzyme-Linked ImmunoSpot assay (ELISPOT) to measure influenza-specific cell-mediated immunity within the FLUCOP consortium
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.984642
Abstract: Influenza continues to be the most important cause of viral respiratory disease, despite the availability of vaccines. Today’s evaluation of influenza vaccines mainly focuses on the quantitative and functional analyses of antibodies to the surface… read more here.
Keywords: influenza specific; influenza; ifn; harmonization qualification ... See more keywords