Learning from –omics strategies applied to uncover Haemophilus influenzae host-pathogen interactions: Current status and perspectives
Sign Up to like & getrecommendations! Published in 2021 at "Computational and Structural Biotechnology Journal"
DOI: 10.1016/j.csbj.2021.05.026
Abstract: Haemophilus influenzae has contributed to key bacterial genome sequencing hallmarks, as being not only the first bacterium to be genome-sequenced, but also starring the first genome-wide analysis of chromosomes directly transformed with DNA from a… read more here.
Keywords: influenzae host; pathogen; influenzae; haemophilus influenzae ... See more keywords
Evaluation of the adequacy of the antimicrobial therapy of invasive Haemophilus influenzae infections: A pharmacokinetic/pharmacodynamic perspective.
Sign Up to like & getrecommendations! Published in 2020 at "Enfermedades infecciosas y microbiologia clinica"
DOI: 10.1016/j.eimc.2020.05.025
Abstract: INTRODUCTION In Europe, non-typeable H. influenzae (NTHi) is the leading cause of invasive H. influenzae disease in adults and is associated with high mortality. The goal of this study was to determine whether current antimicrobial… read more here.
Keywords: influenzae; probability; antimicrobial therapy; evaluation adequacy ... See more keywords
Rapid and direct molecular detection of Streptococcus pneumoniae and Haemophilus influenzae isolated in oropharynx and nasal cavity of children
Sign Up to like & getrecommendations! Published in 2020 at "New Microbes and New Infections"
DOI: 10.1016/j.nmni.2019.100632
Abstract: There is a direct correlation between asymptomatic oropharyngeal colonization by pathogenic bacteria and the prevalence of paediatric respiratory infections. Streptococcus pneumoniae and Haemophilus influenzae are common cause of serious bacterial infections such as meningitis in… read more here.
Keywords: pneumoniae haemophilus; pneumoniae influenzae; influenzae; haemophilus influenzae ... See more keywords
P-1145. Geographic and Genetic Similarities between Sporadic Haemophilus influenzae Type b Pediatric Meningitis Cases in New York City
Sign Up to like & getrecommendations! Published in 2025 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofae631.1332
Abstract: Abstract Background Two unvaccinated infants residing in Brooklyn, NY presented to our hospital with Haemophilus influenzae type b (Hib) meningitis within one year of each other. Prior outbreak data suggest that communities with low vaccination… read more here.
Keywords: epidemiology; hib; type; meningitis cases ... See more keywords
Multiclonal Expansion and High Prevalence of β-Lactamase-Negative Haemophilus influenzae with High-Level Ampicillin Resistance in Japan and Susceptibility to Quinolones
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DOI: 10.1128/aac.00851-18
Abstract: β-Lactam-resistant Haemophilus influenzae is a clinical concern. A high prevalence (>40%) of β-lactamase-negative high-level ampicillin-resistant H. influenzae (high-BLNAR) isolates in Japan has been reported. ABSTRACT β-Lactam-resistant Haemophilus influenzae is a clinical concern. A high prevalence… read more here.
Keywords: lactamase negative; influenzae; high blnar; prevalence ... See more keywords
Utility of Polymerase Chain Reaction in Nasopharyngeal Swabs for Identifying Respiratory Bacteria Causing Community-Acquired Pneumonia
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00379-22
Abstract: Timely identification of a pathogen in patients with lower respiratory tract infections is of paramount importance to avoid inappropriate antibiotic prescription. We aimed to evaluate the performance of a rapid syndromic molecular assay in nasopharyngeal… read more here.
Keywords: lower respiratory; influenzae; tract infections; filmarray ... See more keywords
Antimicrobial Susceptibility Survey of Invasive Haemophilus influenzae in the United States in 2016
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02579-21
Abstract: Antibiotics play an important role for the treatment and prevention of invasive Haemophilus influenzae disease. Antimicrobial resistance survey of invasive H. influenzae isolates collected in 2016 showed that the US H. influenzae population remained susceptible… read more here.
Keywords: influenzae; invasive haemophilus; haemophilus influenzae; susceptibility ... See more keywords
Whole-genome sequencing of non-typeable Haemophilus influenzae isolated from a tertiary care hospital in Surabaya, Indonesia
Sign Up to like & getrecommendations! Published in 2024 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-024-09826-8
Abstract: Haemophilus influenzae causes life-threatening invasive diseases such as septicaemia and meningitis. Reports on circulating H. influenzae causing invasive disease in lower-middle income settings, including Indonesia, are lacking. This study describes the serotype distributions and whole-genome… read more here.
Keywords: surabaya indonesia; whole genome; influenzae isolated; hospital surabaya ... See more keywords
Haemophilus influenzae global epidemiology and antimicrobial susceptibility patterns including ampicillin and amoxicillin-clavulanate resistance based on β-lactamase production, 2013–2022
Sign Up to like & getrecommendations! Published in 2025 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-025-11438-9
Abstract: The β-lactam susceptibility of Haemophilus influenzae varies globally due to resistance mechanisms such as β-lactamase production or alteration in Penicillin-Binding Protein 3 (PBP3). Monitoring and understanding these resistance trends are crucial for guiding effective treatment… read more here.
Keywords: epidemiology; resistance; lactamase; susceptibility ... See more keywords
An invasive Haemophilus influenzae serotype b infection in an Anglo-Saxon plague victim
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DOI: 10.1186/s13059-021-02580-z
Abstract: Background The human pathogen Haemophilus influenzae was the main cause of bacterial meningitis in children and a major cause of worldwide infant mortality before the introduction of a vaccine in the 1980s. Although the occurrence… read more here.
Keywords: plague; haemophilus influenzae; influenzae; anglo saxon ... See more keywords
CRISPRi-seq in Haemophilus influenzae reveals genome-wide and medium-specific growth determinants
Sign Up to like & getrecommendations! Published in 2025 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1013650
Abstract: Work in the human pathobiont Haemophilus influenzae has pioneered functional genomics in bacteria such as genome-wide transposon mutagenesis combined with deep sequencing. These approaches unveiled a large set of likely essential genes, but functional studies… read more here.
Keywords: genome wide; crispri seq; growth; haemophilus influenzae ... See more keywords