Coevolving residues inform protein dynamics profiles and disease susceptibility of nSNVs
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DOI: 10.1371/journal.pcbi.1006626
Abstract: The conformational dynamics of proteins is rarely used in methodologies used to predict the impact of genetic mutations due to the paucity of three-dimensional protein structures as compared to the vast number of available sequences.… read more here.
Keywords: coevolving residues; protein dynamics; conformational dynamics; inform protein ... See more keywords