HBB-deficient Macaca fascicularis monkey presents with human β-thalassemia
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DOI: 10.1007/s13238-019-0627-y
Abstract: β-Thalassemia is a common severe genetic disease caused by mutations in HBB and affects approximately 1.5% of the global population (Origa, 2017). In southern China, the carrier rate of β-thalassemia is as high as 6.43%,… read more here.
Keywords: monkey; hbb; information fig; thalassemia ... See more keywords
Ciliary defects caused by dysregulation of O-GlcNAc modification are associated with diabetic complications
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DOI: 10.1038/s41422-018-0114-7
Abstract: Dear Editor Diabetes is a chronic metabolic disease that has become a major epidemic worldwide. High blood glucose is thought to be the primary cause of most devastating long-term complications of diabetes. In addition to… read more here.
Keywords: ciliogenesis; information fig; supplementary information; glcnacylation ... See more keywords
The cell surface marker CD36 selectively identifies matured, mitochondria-rich hPSC-cardiomyocytes
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DOI: 10.1038/s41422-020-0292-y
Abstract: Dear Editor, Human pluripotent stem cell (hPSC)-derived cardiomyocytes (CMs) are of significant translational value to in vitro studies of human cardiac development, drug and cardiotoxicity testing and cardiac disease modelling. Differentiation of hPSCs to CMs,… read more here.
Keywords: cd36; information fig; cms; supplementary information ... See more keywords