Pharmacokinetic equations versus Bayesian guided vancomycin monitoring: Pharmacokinetic model and model‐informed precision dosing trial simulations
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DOI: 10.1111/cts.13210
Abstract: The recently released revised vancomycin consensus guideline endorsed area under the concentration‐time curve (AUC) guided monitoring. Means to AUC‐guided monitoring include pharmacokinetic (PK) equations and Bayesian software programs, with the latter approach being preferable. We… read more here.
Keywords: guided monitoring; model; informed precision; bayesian guided ... See more keywords
Model-Informed Precision Dosing of Antibiotics in Pediatric Patients: A Narrative Review
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DOI: 10.3389/fped.2021.624639
Abstract: Optimal pharmacotherapy in pediatric patients with suspected infections requires understanding and integration of relevant data on the antibiotic, bacterial pathogen, and patient characteristics. Because of age-related physiological maturation and non-maturational covariates (e.g., disease state, inflammation,… read more here.
Keywords: narrative review; precision dosing; model informed; drug ... See more keywords