Near-infrared-activated Ru(II)-nile blue conjugates as type-I photosensitizers for efficient hypoxia tumor therapy.
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DOI: 10.1039/d5cc03927d
Abstract: Two cyclometalated Ru(II) complexes functionalized with a modified Nile Blue derivative were developed as near-infrared (NIR)-activated photosensitizers. These complexes efficiently generate superoxide anion radicals (O2˙-) via a type-I mechanism upon irradiation with highly-penetrating 730 nm… read more here.
Keywords: blue conjugates; activated nile; nile blue; tumor ... See more keywords
Exploring photo-excited states of aromatic sulfones for efficient near-infrared-activated photothermal cancer therapy
Sign Up to like & getrecommendations! Published in 2025 at "Bulletin of the Chemical Society of Japan"
DOI: 10.1093/bulcsj/uoae137
Abstract: Near-infrared light activation enhances phototherapeutic efficacy due to deep-tissue penetration and minimal invasion. While near-infrared-phototherapeutic agents are widely studied, conventional designs often increase molecular size, affecting pharmacokinetics. This study elucidates the photo-excited states of sulfone-containing… read more here.
Keywords: cancer; photo excited; efficient near; infrared activated ... See more keywords