The ING1a model of rapid cell senescence
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DOI: 10.1016/j.mad.2018.06.004
Abstract: Replicative capacity of normal human cells decreases as telomeric sequence is lost at each division. It is believed that when a subset of chromosomes reach a critically short length, an ATM-initiated and p53-mediated transcriptional response… read more here.
Keywords: senescence; ing1a model; cell senescence;