Prediction of acute inhalation toxicity using cytotoxicity data from human lung epithelial cell lines
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4090
Abstract: Recent research on in vitro systems has focused on mimicking the in vivo situation of cells within the respiratory system. However, few studies have predicted inhalation toxicity using conventional and simple submerged two‐dimensional (2D) cell… read more here.
Keywords: toxicity using; inhalation toxicity; acute inhalation; inhalation ... See more keywords
In vitro model for predicting acute inhalation toxicity by using a Calu-3 epithelium cytotoxicity assay.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmacological and toxicological methods"
DOI: 10.1016/j.vascn.2019.04.002
Abstract: INTRODUCTION As the current methods to predict the inhalation toxicity of chemicals using animal models are limited, alternative methods are required. We present a new in vitro prediction method for acute inhalation toxicity using the… read more here.
Keywords: cytotoxicity assay; epithelium; inhalation toxicity; acute inhalation ... See more keywords
Acute inhalation toxicity of aerosolized electrochemically generated solution of sodium hypochlorite
Sign Up to like & getrecommendations! Published in 2021 at "Inhalation Toxicology"
DOI: 10.1080/08958378.2021.2013348
Abstract: Abstract Objective The objective was to determine the inhalation toxicity of the electrochemically generated sodium hypochlorite solution after its single administration to laboratory animals in the form of a highly dispersed aerosol. Materials and methods… read more here.
Keywords: inhalation; inhalation toxicity; electrochemically generated; toxicity ... See more keywords
Inhalation Toxicity of Talc.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of aerosol medicine and pulmonary drug delivery"
DOI: 10.1089/jamp.2020.1609
Abstract: Respirable talc powder (RTP) is a complex mineral mixture of talc along with accessory minerals, including tremolite, anthophyllite, quartz, magnesite, dolomite, antigorite, lizardite, and chlorite. The industrial mining, milling, and processing of talc ore is… read more here.
Keywords: toxicity talc; inhalation toxicity; talc; inhalation ... See more keywords
A Comparison of Rodent and Nonrodent Laryngeal and Tracheal Bifurcation Sensitivities in Inhalation Toxicity Studies and Their Relevance for Human Exposure
Sign Up to like & getrecommendations! Published in 2017 at "Toxicologic Pathology"
DOI: 10.1177/0192623316678695
Abstract: In inhalation toxicity studies, drug-induced lesions are frequently reported in the larynx and sometimes at the tracheal bifurcation (carina) in the rat, but less so in the dog or monkey, bringing into question the relevance… read more here.
Keywords: inhalation toxicity; tracheal bifurcation; rodent; rodent nonrodent ... See more keywords
In vitro Alternatives to Acute Inhalation Toxicity Studies in Animal Models—A Perspective
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00549
Abstract: When assessing the risk and hazard of a non-pharmaceutical compound, the first step is determining acute toxicity, including toxicity following inhalation. Inhalation is a major exposure route for humans, and the respiratory epithelium is the… read more here.
Keywords: inhalation toxicity; toxicity; vitro alternatives; acute inhalation ... See more keywords
Assessment of acute inhalation toxicity of citric acid and sodium hypochlorite in rats
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Veterinary Science"
DOI: 10.4142/jvs.22253
Abstract: Background Citric acid (CA) and sodium hypochlorite (NaOCl) have been used to disinfect animals to protect them against avian influenza and foot-and-mouth disease. Objectives We performed a good laboratory practice (GLP)-compliant animal toxicity study to… read more here.
Keywords: citric acid; inhalation toxicity; acid sodium; toxicity ... See more keywords
Twenty-Eight-Day Repeated Inhalation Toxicity Study of Nano-Sized Neodymium Oxide in Male Sprague-Dawley Rats
Sign Up to like & getrecommendations! Published in 2017 at "Toxicological Research"
DOI: 10.5487/tr.2017.33.3.239
Abstract: Neodymium is a future-oriented material due to its unique properties, and its use is increasing in various industrial fields worldwide. However, the toxicity caused by repeated exposure to this metal has not been studied in… read more here.
Keywords: day; nano sized; inhalation toxicity; sized neodymium ... See more keywords