Inhaled tobramycin for chronic infection with pseudomonas aeruginosa in non-cystic fibrosis bronchiectasis: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2020.106283
Abstract: INTRODUCTION Non-cystic fibrosis bronchiectasis (NCFBE) is a chronic and progressive disease characterized by the permanent destruction of small and mid-sized airways. Many patients are chronically colonized by Pseudomona aueruginosa, for which oral antibiotics are given.… read more here.
Keywords: non cystic; cystic fibrosis; fibrosis bronchiectasis; inhaled tobramycin ... See more keywords
Simulated Intravenous versus Inhaled Tobramycin with or without Intravenous Ceftazidime Evaluated against Hypermutable Pseudomonas aeruginosa via a Dynamic Biofilm Model and Mechanism-Based Modeling
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DOI: 10.1128/aac.02203-21
Abstract: Acute exacerbations of chronic respiratory infections in patients with cystic fibrosis are highly challenging due to hypermutable Pseudomonas aeruginosa biofilm formation and resistance emergence. We aimed to systematically evaluate the effects of intravenous versus inhaled… read more here.
Keywords: intravenous ceftazidime; ceftazidime; combination; biofilm ... See more keywords
Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis: a randomised, controlled clinical trial
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DOI: 10.1136/thoraxjnl-2021-217782
Abstract: Rationale Inhaled tobramycin and oral azithromycin are common chronic therapies in people with cystic fibrosis and Pseudomonas aeruginosa airway infection. Some studies have shown that azithromycin can reduce the ability of tobramycin to kill P.… read more here.
Keywords: azithromycin; placebo; cystic fibrosis; inhaled tobramycin ... See more keywords
Clinical improvement in Job syndrome following administration of co-trimoxazole, omalizumab and inhaled tobramycin.
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DOI: 10.5603/arm.a2021.0079
Abstract: Established treatment regimens for the autosomal dominant hyperimmunoglobulin E syndrome, denominated Job syndrome, are lacking. Thus, Job syndrome still exerts a dramatic impact on patients' quality of life. Our aim was to present safety and… read more here.
Keywords: trimoxazole omalizumab; job; job syndrome; inhaled tobramycin ... See more keywords