Upregulation of INHBA mediated by the transcription factor BHLHE40 promotes colon cancer cell proliferation and migration
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24539
Abstract: Colon cancer is highly prevalent, and cell proliferation and migration are major reasons for its progression to malignancy. The upregulation of INHBA, a glycoprotein hormone that regulates the secretion of pituitary hormones, is documented to… read more here.
Keywords: proliferation; inhba; colon cancer; migration ... See more keywords
microRNA-6785-5p-loaded human umbilical cord mesenchymal stem cells-derived exosomes suppress angiogenesis and metastasis in gastric cancer via INHBA.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119222
Abstract: OBJECTIVE Exosomes (Exos) are known to transfer microRNAs (miRNAs) to participate in human diseases. We aim to identify the role of human umbilical cord mesenchymal stem cells (HUCMSCs)-derived Exos (HUCMSC-Exos) conveying miR-6785-5p in gastric cancer… read more here.
Keywords: angiogenesis; mir 6785; inhba; human umbilical ... See more keywords
microRNA-211-mediated targeting of the INHBA-TGF-β axis suppresses prostate tumor formation and growth
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Gene Therapy"
DOI: 10.1038/s41417-020-00237-w
Abstract: Prostate cancer (PCa) stem cells increase the sustainability of tumor growth, resulting in high relapse rates in patients with PCa. This goal of the present study was to elucidate the function of microRNA (miR)-211 in… read more here.
Keywords: tumor; inhba; pca stem; mir 211 ... See more keywords
Circular RNA 0000654 facilitates the growth of gastric cancer cells through absorbing microRNA-149-5p to up-regulate inhibin-beta A
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2009414
Abstract: ABSTRACT Circular (circ) RNAs are differentially expressed in gastric cancer (GC) and participate in the biological growth of tumor cells. Given that, investigations were performed to unravel the function of circ_0000654 in GC. GC tissue… read more here.
Keywords: growth; circ 0000654; mir 149; inhba ... See more keywords
Impaired angiogenesis in diabetic critical limb ischemia is mediated by a miR-130b-INHBA signaling axis.
Sign Up to like & getrecommendations! Published in 2023 at "JCI insight"
DOI: 10.1172/jci.insight.163041
Abstract: Patients with peripheral artery disease (PAD) and diabetes constitute a high risk population for development of critical limb ischemia (CLI) and amputation, although the underlying mechanisms remain poorly understood. Comparison of dysregulated microRNAs from diabetic… read more here.
Keywords: limb; limb ischemia; inhba; mir 130b ... See more keywords
Clinical Significance of INHBA Gene Expression in Patients with Gastric Cancer who Receive Curative Resection Followed by Adjuvant S-1 Chemotherapy.
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DOI: 10.21873/invivo.11095
Abstract: BACKGROUND Standard treatment for stage II/III gastric cancer is curative resection followed by adjuvant chemotherapy. However, the five-year survival remains unsatisfactory. Inhibin βA (INHBA) has been reported to be associated with cancer cell proliferation and… read more here.
Keywords: adjuvant chemotherapy; gastric cancer; inhba; expression ... See more keywords