Epigenome in Early Mammalian Development: Inheritance, Reprogramming and Establishment.
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DOI: 10.1016/j.tcb.2017.10.008
Abstract: Drastic epigenetic reprogramming takes place during preimplantation development, leading to the conversion of terminally differentiated gametes to a totipotent embryo. Deficiencies in remodeling of the epigenomes can cause severe developmental defects, including embryonic lethality. However,… read more here.
Keywords: mammalian development; development inheritance; inheritance reprogramming; epigenome early ... See more keywords