A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease
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DOI: 10.1038/s41591-020-0781-z
Abstract: Development of tau-based therapies for Alzheimer’s disease requires an understanding of the timing of disease-related changes in tau. We quantified the phosphorylation state at multiple sites of the tau protein in cerebrospinal fluid markers across… read more here.
Keywords: alzheimer disease; inherited alzheimer; disease; pathology ... See more keywords