Genetics of Inherited thrombocytopenias.
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DOI: 10.1182/blood.2020009300
Abstract: The inherited thrombocytopenia syndromes are a group of disorders characterized primarily by quantitative defects in platelet number, though with a variety demonstrating qualitative defects and/or extra-hematopoietic findings. Through collaborative international efforts applying next generation sequencing… read more here.
Keywords: genetics inherited; inherited thrombocytopenias; etiology; genetics ... See more keywords
Eltrombopag for the treatment of inherited thrombocytopenias: a phase II clinical trial
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DOI: 10.3324/haematol.2019.223966
Abstract: Patients with inherited thrombocytopenias often require platelet transfusions to raise their platelet count before surgery or other invasive procedures; moreover, subjects with clinically significant spontaneous bleeding may benefit from an enduring improvement of thrombocytopenia. The… read more here.
Keywords: platelet count; eltrombopag; treatment; inherited thrombocytopenias ... See more keywords
Inherited thrombocytopenias: history, advances and perspectives
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DOI: 10.3324/haematol.2019.233197
Abstract: Over the last 100 years the role of platelets in hemostatic events and their production by megakaryocytes have gradually been defined. Progressively, thrombocytopenia was recognized as a cause of bleeding, first through an acquired immune… read more here.
Keywords: thrombocytopenias history; history advances; inherited thrombocytopenias; advances perspectives ... See more keywords
Treatment of inherited thrombocytopenias
Sign Up to like & getrecommendations! Published in 2022 at "Haematologica"
DOI: 10.3324/haematol.2022.280856
Abstract: The new techniques of genetic analysis have made it possible to identify many new forms of inherited thrombocytopenias (IT) and study large series of patients. In recent years, this has changed the view of IT,… read more here.
Keywords: inherited thrombocytopenias; treatment inherited;