Glucosyl Platinum(II) Complexes Inhibit Aggregation of the C-Terminal Region of the Aβ Peptide
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DOI: 10.1021/acs.inorgchem.1c03540
Abstract: Neurodegenerative diseases are often caused by uncontrolled amyloid aggregation. Hence, many drug discovery processes are oriented to evaluate new compounds that are able to modulate self-recognition mechanisms. Herein, two related glycoconjugate pentacoordinate Pt(II) complexes were… read more here.
Keywords: inhibit aggregation; platinum complexes; terminal region; complexes inhibit ... See more keywords
Coumarin derivatives inhibit the aggregation of β-lactoglobulin
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DOI: 10.1039/d2ra01029a
Abstract: The binding of a small molecule to a protein through non-covalent interactions mainly depends on its size and electronic environment. Such binding can change the stability of the three dimensional protein structure which sometimes may… read more here.
Keywords: inhibit aggregation; aggregation; derivatives inhibit; lactoglobulin ... See more keywords