Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Escherichia coli Producing OXA-48.
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DOI: 10.1021/acsinfecdis.1c00501
Abstract: Despite the advances in β-lactamase inhibitor development, limited options exist for the class D carbapenemase known as OXA-48. OXA-48 is one of the most prevalent carbapenemases in carbapenem-resistant Enterobacteriaceae infections and is not susceptible to… read more here.
Keywords: inhibit oxa; inhibitor development; escherichia coli; carbapenemase ... See more keywords